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Volume 53, Issue 4, 2025

Online ISSN: 2560-3310

ISSN: 0350-8773

Volume 53 , Issue 4, (2025)

Published: 30.06.2025.

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01.01.2007.

Original scientific paper

CARDIAC DYSRRHYTHMIAS IN HYPERTENSIVE PATIENTS WITH LEFT VENTRICULE HYPERTROPHY

Cardiac dysrrhythmias can be found in patient with no signs of ischemic cardiac disease but supraventricular and ventricular arrhythmias can be developed in cardiac hypertrophy. In this work we have examined frequency of cardiac dysrrhythmias in patients with hypertension and with or without hypertrophy of left ventricule (LVH). Investigation was accomplished on 80 patients with high blood pressure. In all 80 patients, basic on ECHO signs we define LVH, and by using of Holter monitoring we analised dysrrhythmias. Basic on ECHO signs we have 2 groups of patients: I.group ECHO (+) LV, and II group ECHO (-) LVH, in each 40 patients. Holter monitoring have 37 patients [22 mans (59,45%) and 15 women (40,54%)]. Hypertensive patients with LVH, who hade dysrrhythmia, have middle value IMLV 155,3 ± 27,21; аgе 56,42 ± 6,04; duration of hypertension 11,73 ±10,05; and EF% 55,2 ± 3,77. In patients with Holter monitoring 16 ( 43,32%) have dysrrhythmias type II, IIIa, IIIb and IV Lowny degree, (12) 34,43% from 43,32% have LVH. Salves VES are registrated only in group hypertension patients with ECHO(+) 5,4%. By using Mann Whitney statistic test for presents of dysrrhythmias in 2 groups of patients (ECHO LVH and ECHO without LVH), we found statistics significants (p = 0,049). In IMLV 60-110 g/m² 8,82% patients have dysrrhythmia, IMLV 151-200 g/m² dysrrhythmias are registrated in 40%; and 50% patients have dysrrhythmias in IMLV> 200g/m². In group hypertensive patients with LVH dysrrhythmias are registrated in group with ecscentric LVH 35,1%

M. Šipić, D. Čelić, B. Krdžić, V. Perić, J. Krdžić

01.01.2007.

Original scientific paper

THE INFLUENCE OF ENVIROMENT AND EDUCATION ON INFORMATION ABOUT HORMONAL SUPSTITUTIONAL THERAPY (HST) IN MENOPAUSE

Menopause is a physiological condition arising from the end of a woman's reproductive life and is defined by the gradual decline of menstrual bleeding over a period of 12 months. Hormone Replacement Therapy (HRT) is the first choise therapy in treating this condition, and prevention of early and late problems associated with hormone deficient in menopause. This study was organized on Clinics for Gynecology and obstretics in Novi sad. We were examined women knowledge about HRT, as the number of active users of HRT. Two hundred testing women were divided into two groups, arrived from city or willage regions, and they had different education level. Our results showed that number of examined persons, who were infomed about HRT, was significantly higher in city region, but number of HRT users was nearly the same for both groups. Education degree is the significant factor associated with information about HRT. High education women were better informed according to women with lower education. Irrecpective of origin and educational degree, there was statisticaly little number of women, who use HRT, despite of their aknowlegment about this way of therapy. According to our results, we conclude that, it is very important to conduct a proffesional aproach, including continual preventive action, for resolving hesitation to HRT

D. Stajić, M. Bujas, S. Stević

01.01.2007.

Original scientific paper

CHANGES OF ANTHROPOMETRIC PARAMETERS OF THE THIGH DURING PROGRAMMED STRENGTH TRAINING

Primary stimulus for muscular mass enlargement is to repeat developing of sceletal muscles force in the level above the one which exist in everyday activities. The aim of this work was following the growth of lower leg extensor muscular force as well as changes in the surface of a diagonal upper leg muscular tissue cross-section during eight-week programming force training. 12 male subjects, who were neither active nor regular in practicing sport for the last six months, were included in this examination. Conducted training programme was based on dynamic lower leg extensor muscular force training with concentric and eccentric component. Programme was consisted of three training a week for the period of eight weeks. Anthropometric measuring of the upper leg as well as upper leg skin folds ranges were conducted before the th beginning of training programme, after 4 week and at the end of training programme, and also calculated the surface size of diagonal upper leg pure muscular mass cross-section. During eight-week training, we have statistically significant growth th th of lower leg extensor muscular force (27.20% in 4 week, 50.18% in 8 week). After four-week training, we have statistically enlargement in the surface of diagonal left and right upper leg muscular tissue cross-section for 2.62% and 2.45%. This dimension continued to grow by 8th week of training (7.63% and 7.07%). Programming force training with concentric and eccentric component has lead to significant muscular force growth as well as surface enlargement of diagonal upper leg muscular tissue cross-section in previously untrained person. Muscular mass enlargement was more th th important at the end of 8 week than after 4 week

O. Barak, J. Popadić Gaćeša, M. Drapšin, D. Karaba Jakovljević, A. Klašnja

01.01.2007.

Original scientific paper

CHARACTERISTICS OF ALCOHOLISED DRIVERS BASED ON ESTABLISHED ALCOHOL CONCENTRATION IN EXHALED AIR

This research has been done on a sample of 4211 drivers, from which 3886 ( 92,28%) were put in examination for plus measuring alcohol concentration in exhaled air, that is, breath testing with breathalyser type Alcotest® 7410 RS, while 297 of examined people, besides breath testing were put through blood sample analysis, applying ADH enzyme's method. Both sexes were covered in this examination, and they were at the age from 16 to 66, classified according to the clinical phase alcohol taken. Results: Most of the alcoholic drivers were men. The greatest number (94,9% from 4211) didn't participate in a traffic accidents (TA), 3,8% were participants in TA with material damage, and in 1,2% of cases were TA with injuring some of the participants, while in just 4 cases (0,1%) came to mortal injuring participants. The highest number of police controls were registrated on Saturdays, in Summer months, in time from 00:00 to 03:59 hours. Average age of the examined people were 32,5 years old (SD = 0,871), and the greatest number of the examined in this analysed sample belongs to age group from 21 to 30 (1748, that is, 41,51% from 4211). The greatest number of drivers (51,3%) were in clinical phase of mild intoxication. Applying three factor's ANOVA statistical method with one set factor (with part of a day in a month) it is established that arising traffic accidents (TA) depends solely from clinical phase of intoxication. Obtained results taken from breath testing are compared with results received from determinating Blood Alcohol Concentration (BAC) applying enzym's ADH method. Very high coefficient of correlation is established from 0,95 (r 0,198, p>0,0006). In the observed period falling trend of alcoholic drivers is recorded. We can note constant numerical domination of age group of 21 to 30. Driving drunken is typical characteristic for male population. In group of professional drivers it's extremely rare steering a vehicle in alcoholic condition. It is detected that in most cases of TA participants were in mild or medium state of intoxication, what indicates to a major accidental significance precisely these degrees of intoxication

M. Milošević, S. Savić, S. Matejić, P. Mandić, Z. Mihailović, V. Jakšiċ, S. Dobričanin

01.01.2007.

Case Reports

DIFFICULT INTUBATION IN CAESAREAN SECTION

Every situation where an experienced anesthesiologist needs more than 10 minutes or three tries for putting the endotracheal tube is considered as difficult intubation. Frequency of difficult intubation in pregnant women is three to ten times bigger than general surgical population. This case report shows that it is necessary to have passable respiratory tract in case of difficult intubation in order to keep in life a woman who needs to be done Caesarean section and save mother and a newborn

K. Grujić, M. Cveković, G. Relić

01.01.2007.

History of medicine

BEGINNING DEVELOPMENT BEGINNING DEVELOPMENT OF MEDICAL MEDICAL BIOCHEMISTR BIOCHEMISTRY OF SERBIA

After beeing liberated from the Turkish rule and establishing autonomy (self-gaverment ) serbian elite with big steaps theadet toward developing: social, economical and political lise in Serbia. About had time started to rise and developt official medical servis in principality of Serbia, under it's wing started to originate and medical biocemistry. The gool of this study is to point out and shear new light on istory of medical biohemistry in Serbia using adecvate literure and un publiehed archive documentacion

Slavica Ristić, Siniša Ristić, Lj. Smiljić, S. Medenica, S. Medenica

01.12.2007.

Original scientific paper

HEART INSUFFICIENCY IN ACUTE MYOCARDIAL INFARCTION

Heart insufficiency is frequent and important complication of acute myocardial infarction (AMI). Aim of this work was to estimate frequency, haevyness and course of heart insufficiency in patients with AMI who were different treated in initial phase of AMI, based on what they were separated in three different therapeutic groups: group treated with thrombolytic therapy, group treated with beta-blockers and group treated with nitrates. It was shown that time of admission and condition of patient in moment of admission is the key factor for choise of therapy but using of therapy making less frequency and heavyness of heart insufficiency while for cases with most difficult forms of insufficiency of heart as a pump thrombolytic therapy is practically only posible choice

Z. Marčetić, S. Sovtić, Z. Stašević, D. Đikić, G. Antić, S. Vasić, T. Novaković, D. Rašić, S. Lazić, M. Šipić, V. Perić

01.12.2007.

Professional paper

STRATEGIES IN THE PREVENTION OF NONSTEROIDALANTIINFLAMMATORY DRUGS INDUCED COMPLICATIONS IN THE GASTROINTESTINAL TRACT

Nonsteroidal antiinflamatory drugs are currently one of the most widely used categories of drugs, because there is a huge number of indication for theirs purpose. This huge purpose of this drugs has theirs own price, which is shown in side effects, especialy in the upper parts of gastrointestinal tract: erosions of the mucose in 35-60 %, ulcers in 10-25%, strong bleeding or perforation in <1%. It is appears that this drugs are responsible for 10-20 thousands lethal outcome in the world. Even small dose of acetlisalicil acid by 75 mg,which is used in prevention of cardiovascular disease, brings to the damage of mucose GIT and 11% have ulcer. Inhibition ciklooxigen-1,which have main role in protection mucose of stomach and duodenum on the part of NAIL, lead to damage mucose GIT, and that is the result of sistemic inhibition, which is indenpendant of the way of getting drugs. Some author instigate a local effect of Nail,as week acid. It is necessary to protect highrisk pacient with using gastroprotektiv drugs

B. Dejanović

01.12.2007.

Professional paper

EFFICACY OF PLANT KINGDOM ON STRESS - ULCER DEVELOPING

Despite progress in conventional pharmacology in producing effective drugs, the plant kingdom might provide a useful source of new anti-ulcer compounds for development pharmaceutical entities or, alternatively, as simple dietary adjuncts to existing therapies. Botanical compounds with anti-ulcer activity include flavonoids(i.e.quercetin, naringin, silymarin, anthocyanosides, sophoradin derivatives) saponins (i.e. from Panax japonicus and Kochia scoparia), tannins (i.e. from Linderae umbellatae), gums and mucilages (i.e. gum guar and myrrh). This article reviews the gastro-protective and anti-ulcer properties of the most commonly employed herbal medicines and their identified active constituents. Among herbal drugs, liquorice, aloe gel and capsicum (chilli) have been used extensively and their clinical efficacy documented, but тhe documented literature has centred primarily on pharmacological action in experimental animals.

S. Janićijević-Hudomal, D. Dekanski, J. Rašić

01.12.2007.

Professional reviews

A-MOD ULTRASONOGRAPHYIN DIAGNOSIS OF MAXILLARYSINUSES DISEASES

There are many forms of physical energy which, during such a short period of time, had rich history and which found wide application in the science of medicine, as was the case with the ultrasound in the last fifty years or so. The ultrasound got its affirmation rather soon, as valuable biologically harmless method used for detecting and explaining various pathological conditions in the science of medicine, and therefore in otorhinolaryngology as well. In the following study, the technique of the ultrasound examination of paranasal sinuses is described in details, standard echogramic patterns are
represented, and means of their interpretation are explained as well, regarding the fact that it is not standard. Special focus is
on the literature review whereby the valorization of the ultrasonography in relation to acute and chronic diseases of the maxillary sinuses is performed. In that sense, over 30 extracts by the authors from all parts of the world are represented. The
insight into the results of the latter reports, as well as the author own experiences, lead to the conclusion that the A-mode
ultrasonography represents an impartial method applicable in diagnostics of the maxillary sinus diseases. It is practical and
economical for it is performed quickly and in a rather simple manner. It is an invasive and painless method, comfortable for
the patient. Main advantage in relation to other radiological methods lies in the avoidance of the patient and medical doctor's
exposure to X-rays, therefore the ultrasonography method is a matter of choice for diagnosis of primarily maxillary sinus
acute diseases with children and pregnant women. Due to extraordinary sensitivity in the evaluation of the sinus secret, with
acute diseases it represents valuable, impartial supplementary method. On the other hand, due to weaker peculiarity, with
chronic diseases ultrasonography only represents a selective method

B. Belić

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