Breast cancer remains one of the most common malignancies in women and is one of the leading causes of cancerrelated mortality. Despite the current emphasis on breast conservation, mastectomy rates remain at 30%. Mastectomy is often associated with significant psychological sequelae including distorted body image and sexual dysfunction. Breast restoration is assumed to allow a full emotional and physical recovery from a breast cancer crisis. Autogenous tissue gives the best results, and currently the best technique in most women is probably the free DIEPflap. there is theoretically minimal functional loss, minimal risk of hernia, less postoperative pain, and shorter hospitalization. However, there is a range of options, such as other flaps and use of implants, which can be tailored to specific situations

High frequency of appearance and use of expensive diagnostic and therapeutic methods makes lumbar radiculopathy the most expensive benign disease. The aim of the study was evaluation of types psychological reactions in surgically treated patients with chronic lumbar radiculopathy. Matherial and methods: We examined 50 surgically treated patients who had low back pain. The patients were multidisciplinary examined and treated on Medical Rehabilitation Clinic in Novi Sad. The Minnesota Multiphasic Personal Inventory (MMPI) was used to determine the personality profiles. Patients were tested after rehabilitation treatment. Results of the exploring showed the normal profile of personality in 70 % of patients and pathological profile in 30 % ( hypochondria in 8, hysteria in 5 patients and depression in 2 patients). All groups showed improvement in functional limitation during the rehabilitation treatment. Severity and length of pain after rehabilitation treatment is bigger in the group of patients with pathological profile of personality (p<0,005). Psychological factors may play an important role in the onset, severity, exacerbation, or maintenance of this type of chronic pain. Screening surgically treated patients with chronic lumbar radiculopathy with MMPI may be effective in identifying psychopathology

Transtrochanteric fractures represente ekstracapsular fracture proksimal heel of femur, but sometimes is possible to stretch fracture line in intracapsular area. All this fracture represente large disability for patient, large life threatening and if is don`t have adequate treatment substantially is change quality of life. Most of patient with transtrochanteric fractures is older than 65. years with prevalence women gender in attitude 3:1. Number of patient with fracture proksimal heel of femur and with fracture trochanteric area growing up from year to year. In west country this fracture get epidemic shape. For make work it is used material from department of Orthopaedics and traumatology in Medical centre in Kosovska Mitrovica in interval at 2003. to 2006. years. In process of work we follow frequency patient with transtrochanteric fractures in attitude at gender, age, way of injury. We following time elapsed from fractures to surgery treatment, kind of anesthesia, number of day after operation. In postoperative course following is time verticalization patient, presence early and late complication. The ultimatefunctional results which we receive, were shown according to the modificated scale by Merle d'Aubigneu

Old age can be defined as a variety of changes in structure and function which begin at the stage of reproductive maturity, and that changes are manifested as a lesser ability of adaptation and lesser way of defending from the influence of outside and inside factors. Neurons of sympathetic trunk, as well as the other neuron cells, are changeable during the life. Neurobiological, old age begins at the time of birth, because the number of neurons is not increasing, it's only getting lower, which means that neurons are post mitotic cells. The process of old age is increased with some degenerative changes at some diseases and its hard to know what belongs to, so called, physiologic way of getting old and what is pathologic. Concentration of lipofuscin in cells (pigment of old age), is the parameter for physiologic old age of a person. Concentration is changeable, and it depends from the tissue or the organ, concentration is controlled by the internal regulatory factors and the factors of environment as the way of nutrition, physical activity, stress and hygienic factors.

The aim of work was to find out whether multiparity led to increased morbidity and mortality of mothers multyparous. Special attention was paid to appearance of diseases among mothers, both those developed during pregnancy and immediately after delivery. Multiparity is especially characteristic of women of Albanian nationality. Thus it is obvious that there is a reverse proportion between multiparous women and level of education the higher level of education is the smaller is the number of previous deliveries. There is a significant difference in apsolute number of deliveries according to the place of living in favor of rural residence. Number of both EPH gestoses (Eclampsia, pre-eclampsia) and indications for Caesarian section is increasing with multiparity. Abruption of normaly inserted placenta is significantly more frequent among multiparous women. It is obvious that multiparous women more frequently have bleedings during third and forth delivery period. There were also a large number of hysterectomies during delivery (75). Death rate of women is significantly increasing with multiparity. Eclampsia is the cause of death among more than half of all women. Resuming all data the autor is pointing out that grand multiparity, giving birth to more than six children, is, mfom medical point of view, an increased risk both for a newborn and a pregnant woman. Perinatal motality and morbidity is increased and high risk during pregnancy, delivery and puerperium is simultaneously rising until the pregnant woman's life is seriously endangered

Diabetes mellitus with one`s chronical complications is the cause of the large percent morbidites and mortality, among the population. With regard to a lot of people who have diabetes mellitus tip 2 (WHO-over 170.000.000 peoples), adequate therapy is very important. By this stady, we wont to show positive consequence new therapy for medication diabetes mellitus typ 2, chiefly application tiazolidinedion in therapy. Handlend 25 patientis with diabetes mellitus typ 2 during 3-mounth observed. Patients were divide in II groups forms on basic of the kind therapy. At the end of 3-mounth, derived results (decrease HbA1c from 7.9%±1.24% to 6.99±0.89%; data value fasting glycemia from 8.99mmol/l±2.08 mmol/l to 7.45±1.35 mmol/l, and value glycemia after meal 10.36 mmol/l±2.18 mmol/l to 8.18 mmol/l±1.31 mmol/l) indicate validity the introduction tiazolidinedion in therapy diabetes mellitus type 2.

The aim of this study was to show values of dynamometric parameters in elite athletes, and to determine and explain difference in those parameters between persons of various sport specialities and non sportsmen. In the study were included 153 participants: 123 elite athletes (17 boxers, 17 wrestlers, 27 hockey, 23 volleyball, 20 handball, 20 basketball and 19 soccer players) and 30 students, non sportsmen. Muscular strength (A) and power (P) were registrated by dynamometry. As a result of chronic adaptation to training, athletes had significantly higher values of registered parameters than non sportsmen. Lowest values of dynamometric parameters were measured in non sportsmen, at arm flexion A was 57.65 kg and power P285.60 W. Comparing results of athletes of different sport specialties, significant difference was found in values of some parameters. Dynamometric parameter at arm flexion has had the highest value in tested wrestlers 82.0kg, and lowest values were registered in soccer players, but only in absolute values. Differences in some measured parameters between groups of athletes can be explained by specific demands in different sports, during prolonged training and performance activities

Allergen-specific immunotherapy (SIT) is the practice of administering gradually increasing quantities of an allergen extractto an allergic subject to ameliorate the symptoms associated with the subsequent exposure to the causative allergen. The major objectives of SIT in alergy disorders are, in the short term, to reduce the allergic triggers precipitating symptoms, and, in the long term, to decrease allergy inflammation and nonspecific bronchial hyperreactivity when bronchial remodeling is not prominent. The mechanisms of SIT are complex but it was convincingly shown to act by modifying Th2 cell responses either by immune deviation (increase in Th0/Th1) or T cell anergy (decrease inTh2/Th0) or more likely both. Specific immunotherapy is the only treatment that may alterthe natural course of allergic disease.

In this work we present a basic aspects of ionising radiation (afterward of depleted uranium), this effects to human organism, esspecially on radiobiological, health effects on human skin. Health effects ionising radiation on skin depends of its doses. High doses given stron reaction, already in a few days after radiation, and later manifestations arise after longer exposition lower doses this radiation. In this work we present a basics pathophysiological aspects, without specifical clinical manifestations of radiation dermatitis.

Eosinophilic Granuloma (EG) represent the most benign and localized form of the three Langerhans cell histiocytosis syndromes. In bone, it is a tumor-like proliferation Langerhans cells. Intraosseous EG lesions can be solitary or multifocal. EG accounts for 60-70 % of Langerhans cells histiocytosis cases. The authors are describle a 21 year-old men with Eosinophilic granuloma. The disease had a rarely course with disorders multiple lesions in bones