Rheumatoid arthritis is a complex disease, which produces articular symptoms and damage, leading to disability. The aim of the study was the estimate frequency comorbidity, functional ability of patients with rheumatoid arthritis.This study included 60 patients (48 female and 12 male) with rheumatoid arthritis, mean age 53,92±7,06. Anatomical stage and functional class were analyzed according to Steinbrocker`s criteria. Functional disability was perfo-rmed using health assessment questionnaire (HAQ) score. Comorbidity was observed in 36 (60%) of patients (33 female and 3 male). Hypertension were found in 19 (31,67%) of patients, whereas 8 (13,33%) of patients had diabetes. It was established that 7(11,67%) of patients suffered osteoarthritis. The median HAQ score was 1,25±0,70. Poorer functional status was observed in 40% of the patients with comorbidity (HAQ score ≥2), than in the group of patients without comorbidity (21,67 %). The results of the study are showing large frequency coexisting disease in patients with rheumatoid arthritis. The frequency of hypertension and diabetes was greater comparing to general population. The patients with rheumatoid arthritis show harder anatomical stage and comorbidity and greater functional disability, as compared to the patients without coexisting disease.

Prostatic intraepithelial neoplasia (PIN) is putative premalignant lesions of the prostate. This lesion has role as precuror of prostatic carcinoma (PC), predictive role for PC and high coexistens with PC. Existed two grade of PIN: low grade PIN (LGPIN) and high grade PIN (HGPIN). PC is most important malignacy in man and has high mortality in male. The aim of research was to invastigated morphological comparative patterns of HGPIN and PC. We analyzed biopsy material of 299 cases (cs). We used histopathological metods of investigation. We found HGPIN in 42 cs (14.0%) with mean age 66.3 y and PC in 35 cs (11.7%) with mean age 70.7 y. HGPIN was most frequently in the seventh decade of life (54.8%), and PC in the eight decade (45.4%). Four common pattern of HGPIN were identified: tufting (78.6%), micropapillary (72.8%), cribriform (16.6%) and flat (9.5%). In 21 from 35 cs (60%) with PC was coexistent HGPIN. HGPIN we found in the periferial part in the 22 cs. (52.4%) and in the periurthral part of the prostate in the 12 Cs. (28.6%). HGPIN were multicentric in the 22 cs. (52.4%), in the 15 cs. (68.2%) in the periferial part, and in the 7 cs (31.8%) in the periurethral part of the prostate. PC in the 22 cs (62.9%) was localized in the periferial, and in the 7 cs in the periuretral portion of the prostate. PC was multicentric in 28.6%. Important histological patterns for distinction HGPIN i PC are: disruption of basal cell layer, perineural invasion, mitotic figures, multiple nucleoli, collagenous micronodules, infiltrative growth. HGPIN and PC we found in sufficient percentage. Both lesion were most frequently multicentric, periferial localisation and coexistent. Because of that these lesions needed serious clinical and histological investigations for patients.

Chronic vein insufficiency (CVI) is abnormal functioning of a system of veins resulted from incompetence of vein valves, with or without vein obstruction covering both surface and deep veins. Nowadays there are various standars in the diagnosis of CVI and variations of treatment modalities, which increases the importance of occuracy and foundations of the diagnosis. In the consideration of diagnostic needs of patients with CVI, CEAP classification is suggested. This classification defines clinic categories, etiology of problem, covered anatomical segments and pathological mechanisms of CVI.

+Gz acceleration is unique dynamic stress to organism. Development of this occurrence depends not only to magnitude of acceleration but to onset rate and duration too. The most of former researches pointed to +Gz stress as significant stress to basic physiological mechanisms like cardiovascular and respiratory system. The new study was to examine responses of neuroendocrine and immune system to +Gz stress.

The Early Warning Score is a simple physiological scoring system that can be calculated at the patient's bedside, using parameters which are mesured in the majority of unwell patients. Patients suffering in-hospital cardiac arrest often have abnormal clinical observations documented prior to the arrest. Study objestives:This study assesses wheather these patients have less favourable outcome following in-hospital cardiac arrest. Matherials and the methods:For the present study, the patients' hospital charts were reviewed to identify possible abnormal observations within 8 h prior to the arrest. Results: From the total of 100 patients who sufferd in-hospital cardiac arrest, 64 patients had documentation of vital signs and 9 patients had no documentation of vital signs. Of the patients with documented vital signs 27 (29,7%) had normal vital signs and 64 (70,3%) had abnormal observations. Among these 64 patients the distribution was as follows: 17 patients (13,1%) had respiatory rate below 8 or over 20 per min, 40 (30,8%) had puls rate below 40 or over 140 beats per min, 20 patients (15,4%) had systolic arterial blood pressure below 90 or over 200 mmHg, 5 (3,7%) had temperature (˚C) below 36,1 or over 37,9 ˚C, 20 (15,4%) had oxygen saturation below 90%, 14 (10,8%) had decrease in consciousness and 14 (10,8%) had urine output below 50 ml/2hours). Compared with patients whose EWS were 0-2 (ОR 1,2; 95% CI: 0,935-1,507) patients with EWS 3 or more were 6,5 times more likely to die in first 24 hours (OR: 7,8; 95% CI: 1,205-50,205). Conclusions:Patients with documented clinically abnormal observations prior to in-hospital cardiac arrest have a worse outcome than those without. The main implication of these is that these patients need to be identified in time thereby possibly avoiding arrest. This can also be used when assessing the prognosis of in-hospital patients after achieved ROSC.

In the most prosperous countries, cerebrovascular diseases takes the high third leading position in mortality rate of the population, therefore justifying the name of a ,,mass killer,, speaking of which, its incidence represents un important not only medical but and socially economic problem (only 2-20% sick ones are able to continue with its previous work) Cerebral stroke incidence is 150-200 cases on 100000 persons per year (1). Taking in consideration all the mentioned, we took as the goal of the study, to investigate the impact of the factors at risk, in ethiopatogenesis of the cerebral stroke. Our study was carried out on 40 patients with acute cerebral stroke hospitalized on the Neurology Clinic, KBC Prishtina. Follow up of the factors at risk in atherosclerosis development included: cholesterol, HDLi LDLtriglycerides level in sera, blood and liquor glucoses, glucoses consuming index-IIGM. Descriptive values of the atherosclerosis index also, and the rate of the premorbid illness as the very important factors in development of the cerebral infarct.

The psychotropic drug addiction is steadily increasing in the subpopulation of the young generation. The objective of this paper is to investigate the degree of psychoticism as a disintegrating personality phenomenon. Psychoticism comprises elements of autism, insensitiveness, aggression, asocialisation. This irregularity in cognitive processes was tested on three groups of people: politoxicomaniacs, psychotic patients and a control group. The DELTA test reported convincingly raised dimensions on the scale of psychoticism: general executive functions (GEI), schyzotypical behaviour (SHD) , paranoia (P), and depression (D), as crucial factors not only for developing addiction but also for achieving long - term and stable abstinence. Apilot study retesting of abstinent persons, has confirmed, after a year's treatment, the change in their behaviour ( by improving all the results on DELTAscale of psychoticism).

Autors reports 20 ten old boy received penetrating vulns thorasic with naif at midle linea.subksifoid area. Patient with angina pectoris, hypovolemic shock end cardiac arrest received at department intensive care Clinic hospital centre Prishtine in Gracanica. In cardiogenic arrest under reanimation is introduction in general endotracheal anestesy and intervention surgery. Maden midle sternotomy and verification laesio pericardii under right cordis longth of 20 mm,hematopericard and vulnus at parietis diaphragmalis right ventricular in area septoapicalis.Past evacuation sangui from pericard heart mobilisation and made compresion phingin.Placement closure laesion with cardiorraphia prolen 0000 sec.Cooley.Lesion right pleurae mediastinalis and placement drain in right torasic cavum and drain mediastine in restrosternal area i aspiration undervother sec. Bilay. Fixation sternum with fillum metalicum sec. Kurschner. Reanimation intensive care all time and past realisation complete haemostasis along linae sutturae heart folow up substitution adecquat failure volumen total sangui plasm and cristolid. Realisation total stability hemodinamic and patient move at department intensive care. Control EKG, echocardiography and cardiac ensims 5 and 10 dely psotoperative show fingins corectly. Not signs ischemic laesaoin and disfunction conducti and arrhythmi. Haert pariets is all corectly viability and cinesy.

The authors in this work presented the case of itterative Caesarean Section. In this intervention they had a complication of endotracheal anaesthetic. Although general anaesthetic, according report the most authors, generally appliance anaesthetic during Caesarean Section, this anaesthetic have a certain failure. This are: difficult intubation, intubation in oesophagus, insufficient relaxation on myometrium, risk of depression - foetal’s central nervous system, unadequate reaction on drugs etc. Some authors have a pioritydaju of regional method according safety. Because of that all we believe, that heed is necessary in work and everybody obstetrician must conscious of this risk, like as application generally anaesthetic such as and regional anaesthetic by woman who has just given birth. In this effect we suggest that knowledge and experience of anaesthesiologies are very important.

Obstructive jaundice presents partial or complete blockade in the gall way towards intestinal tract. This blockade is caused by mechanical obstruction in the extrahepatitic bilioductule system. Etiologic factors which cause obstruction of the extrahepatitic gall ways are numerous. One of the reasons of appearing obstructive jaundice is penetration of the cyst parts or cyst sprout into the gall ways. Echinococcus is zoonosis, parasitic disease, caused by echinococcus granulosus, E. multilocolaris, E. vogeli i E. oligarthus. At humans, cystic form of disease caused by E. granulosus appears most frequently, while the alveolar one caused by E. multilocolaris seu alveolaris appears rarely. Aim of the work is to show the importance of the echinococcus cyst of the liver at the appearing of the obstructive jaundice , penetrating the cyst parts or cyst sprout in the gall ways. The patient presented in the work is E.C., male, register number of the disease history 404/05.06.2007, 20 years old, hospitalized at Surgical Clinic because of the surgery of echinococcus cyst on the left liver lobe. Diagnosis was set by abdomen USG, CT of the abdomen, and laboratory analyses. Echinococcus cyst got complicated by its penetration into the gall ways, and manifested by jaundice, the signs of purulent cholangiitis, and bad general state of the patient, so the surgical treatment is absolutely indicated. During the surgery, after the done pericystectomia, cholendochotomia is done because of the enlarged cholangiitis, where the signs of purulent cholangiitis and 5 cyst sprouts are found and removed. Postoperative flow passed normally. Findings of done secondary cholangiography showed normal structure and transience of gall ways, so the T-drain was removed and the patient sent to further home care in a generally and locally good state.