Insulinska rezistencija je stanje udruženo sa genetskom predispozicijom, sedantarnim načinom života i starenjem. Ono je izazvano i podstaknuto gojaznošću. Metabolički sindrom (MS) pak, predstavlja koincidentno postojanje više metaboličkih poremećaja u čijoj se osnovi nalazi insulinska rezistencija. Cilj ovog rada je bio da se utvrde antropometrijske mere kod obolelih od akutnog infarkta miokarda (AIM) sa i bez metaboličkog sindroma. Prospektivnom studijom obuhvaćeno je 77 bolesnika oba pola koji su lečeni zbog AIM u koronarnoj jedinici Interne klinike-Laplje selo KBC-a Priština sa sedištem u Gračanici. Bolesnici sa reinfarktom miokarda nisu uključivani u istraživanje. Od ukupno 77 ispitanika sa AIM 44 ispitanika je imalo MS ili 57,1% dok je 33 ispitanika bilo bez MS, ili 42.9%. Naše istraživanje je pokazalo sledeće: učestalost MS kod ispitanika lečenih zbog AIM je bila 57,1%; u odnosu na polnu zastupljenost nije nađena bitna razlika između ispitanika sa AIM sa i bez MS ; u grupi ispitanika sa AIM i MS muškarci su bili zastupljeniji (63,6%) u odnosu na žene; nije nađena bitna razlika između poređenih grupa ispitanika u odnosu na starosnu zastupljenost ; poređenjem telesne visine i težine između ispitanika sa AIM sa i bez MS nije nađena značajna razlika ; dobijena je bitna razlika između poređenih grupa ispitanika u odnosu na indeks telesne mase-BMI. Prosečna vrednost BMI kod ispitanika sa AIM i MS je bila 29,34 kg/m2.

Peripartalna kardiomiopatija (PPKM) je redak poremećaj srčane slabosti nepoznatog uzroka koji je često fatalan za mlade žene. Javlja u kasnoj trudnoći ili postpartalnom periodu. PPKM može biti teško dijagnostikovati jer simptomi srčane slabosti mogu imitirati one simptome koji se inače javljaju u trudnoći. Prikaz bolesnika,29- godišnja žena, u 38 nedelji gestacije primljena je na odeljenje zbog otežanog disanja, zamora pri minimalnom naporu i osećaja ubrzanog lupanja srca. Na prijemu bleda, lako oznojena i dispnoična, blede kože i vidljivih sluznica. Gojazna. Auskultacijom na plućima bazalno obostrano oslabljen disajni šum uz inspirijumske pukote bazalno desno. Akcija srca je tahikardna (135 /min) , tonovi oslabljeni, ritam galopa, sistolni šum na ictusu 3/6 po Levinu. TA 130/90. Abdomen je iznad ravni g. koša, inspekcijom se uočavaju gravidarne strije. Ekstremiteti bez edema. Elektrokardiogram pokazuje sinusnu tahikardiju sa fr 130/min, pQ 0,10 sec,qr u D3, slaba progresija r zubca od V1-V4, bifazan p talas u V1, povremene VES, nema značajnih ST-T promena. Odmah urađena transtorakalna ehokardiografija (TTE) pokazala je levi ventrikul uvećanih enddijastolnih i endsistolnih dimenzija (EDDLV 82mm, ESDLV 72 mm), uredne debljine zidova, sa globalnom hikpokinezijom i bez regionalnih ispada u kinetici, sa sniženom EF koja je procenjena na oko 25-30%. Tretirana kardiotonicima, diureticima, uz suspstituciju kalijuma, i Antagonistima kalcijuma što dovodi do poboljšanja stanja. Nakon 5 dana trudnoća je završena carskim rezom i rođeno je zdravo žensko dete. Zaključak: Peripartalna kardiomiopatija je oboljenje čija je etologija još uvek nedovoljno rasvetljena, i na na našim prostorima nije tako česta, ali neblagovremena ili zakasnela dijagnoza su fatalni za trudnicu.

Conclusion about efficacious of some medication can be given based on reducing morbidity and mortality in patients treated with that medication.. Aim of this work was to estimate intrahospital mortality in patients with acute myocardial infarction (AMI), role of myocardial reinfarction in that and side effects of medications in patients who were different treated in initial phase of AMI, based on what they were separated in three different therapeutic groups: group treated with thrombolytic therapy, group treated with beta-blockers and group treated with nitrates. It was shown that intrahospital mortality is highest in patients treated with nitrates but there was not significant difference between thera-peutic groups in frequency of myocardial reinfarction while frequency of complications and side effects were in range as in others similar studies.

Heart insufficiency is frequent and important complication of acute myocardial infarction (AMI). Aim of this work was to estimate frequency, haevyness and course of heart insufficiency in patients with AMI who were different treated in initial phase of AMI, based on what they were separated in three different therapeutic groups: group treated with thrombolytic therapy, group treated with beta-blockers and group treated with nitrates. It was shown that time of admission and condition of patient in moment of admission is the key factor for choise of therapy but using of therapy making less frequency and heavyness of heart insufficiency while for cases with most difficult forms of insufficiency of heart as a pump thrombolytic therapy is practically only posible choice

Dysplasio epiphysialis is congenital disorder of ossification and development of epiphysis that lead to deformation of epiphyses. This disorder of is not so frequent (1). Etiology is unknown. It appears in both sexes in the same percent, sporadically, but in the several members of one family also (2). It appears in two forms, polyarticular and oligoarticular. Clinical feature characterize low growing (150-160 cm) with short clumsy fingers, incrassate joints and limited mobility. Especially characteristic of this disorder is discrepancy between low degree of subjective complaints and marked radiological changes. (1). Laboratory findings most often are not specific. Metabolism of calcium and phosphorus is not changed (2). Radiological is characteristic irregular aspect of joint flanges and articulating surfaces and narrowing of the joint spaces, cartilage sclerosis, cystic changes in joints and, not so often periarticular chondromatosis. Vertebral joints if geared manifest platispondilia and ragged of vertebral joints surfaces (2). Conclusion: Dysplasio epiphysialis multiplex is characterized with specific clinical and radiological feature and appearance in jung ages; it is often substitute with primary generalized osteoarthrosis or rheumatoid arthritis (our case). From those reasons it is very important to recognize the specific nature of this disease for the therapeutic and prognostic purpose.