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Volume 53, Issue 4, 2025
Online ISSN: 2560-3310
ISSN: 0350-8773
Volume 53 , Issue 4, (2025)
Published: 30.06.2025.
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Contents
01.01.2009.
Original scientific paper
THE ROLE OF STUFF IN TRANSPORT OF CRITICALY ILL OR INJURED PATIENTS IN OUR CONDITIONS
Quick, proper and efficient transport is an integral part of all measures taken in treatment and effective care of polytraumatized patients. Before or during the transport, without regard to the transportation means, such patients often need their airways to be protected, connection to mechanical ventilation, applying of oxygen, infusion solution, painkillers or some other drugs. Continual monitoring of vital functions is required part of treatment during transport of critically ill or injured patients. Their transport, beside adequate equipment, demands theoretically and practically well trained stuff. In most European countries anesthesiologists have primary role especially in interhospital transport (for example in transport of neurosurgical patient from local to university hospital). Unfotunatelly, in our conditions transport is often carried out by unsufficiently skilled medical stuff without adequate equipment and experience what may have an effect on treatment success and surviva.
A. Pavlović, A. Jovanović, S. Trpković, G. Trajković
01.01.2009.
Original scientific paper
THE FOLLOW UP STUDY AND DYNAMICS OF THE CHANGES IN LIQUOR CONCENTRATION OF THE SEROTONIN AND EPINEPHRINE IN ACUTE CEREBRAL INFARCT
It is obvious that outcome of the cerebral ischemia depends on many of the metabolic reactions that accompany circulatory disturbance, and forcaming neurochemical changes on the cellular level. Cerebral ischemia accompany changes in the neurotransmitters from the group of the biogenic amines, that influence a great deal whole chain of reactions that lead 66 cell to ultimate death. This processes ease up an enables distribution of the cascade reaction in ischemia leisure. To this should be added the fact, that cerebral infarct is followed with selective disturbance on hematoencephal level for 64. monoamines. It is obvious that cerebral infarct involves changes in metabolism of the central neurotransmitters. This changes could have either short or long term consequences on the ischemic process outcome. Therefore our aim in this study was to investigate the influence of the biogenic amines, serotonin and epinephrine as possible markers in estimation of the neural damage, outcome of the ischemic cerebral stroke and clinical presentation throughout correlation in changes of their concentration in liquor. Investigation included 40 patients on hospital treatment on Neurology Clinic of the CHC Pristina. During the follow up study, we estimated changes in concentration levels of the serotonin and epinephrine in liquor throughout different time intervals, correlating to the neurology status, encountering neuroradiology methods CT and MRof the brain, as a criteria in diagnosing acute ischemic cerebral stroke.
S. Čolić, N. Šternić, D. Mirić, G. Trajković, Lj. Smiljić
01.01.2008.
Original scientific paper
THE INFLUENCE OF GENERALANAESTHESIA ON CHANGES ОF ARTERIAL OXYGEN SATURATION SaO2 IN CIGARETTE SMOKERS
Although there is generally world trend in decreasing of number of smokers, expecially in developed part of world, smoking cigarettes still have large importance in morbidity and mortality of modern human population. Taking anamnestics data about smoking habit instruct anaesthesiologist to apply special strategy in general anaesthesia for a reason of possible complications provoked bby a chronic influence of nicotin and other tobbaco ingredients on different organs. In this article we wanted to examine influence of chronic tobbaco smoke exposing on arterial oxygen saturation SaO2 during and short period after general anaesthesia. Research was evaluated on patients in Emergency Center of Clinical Center of Serbia. Patients were divided in two groups (ASAI and II): group I smokers (n=40) and group II nosmokers (n=40). Our investigation has shown no statistical significant difference on SaO2 during general anaesthesia between two experimental groups. Immediately after general anaesthesia and extubation in postoperative period SaO2 dicreases (p<0.001) during transport from operating room to recovery room in both groups of patients,but the level of hypoxemia was significantly higher in smokers group. In this study we demonstrated that tobbaco smoking corellate with postoperative decrease of SaO2 after general anaesthesia, proposing an additional oxygen therapy in early postoperative period.
A. Pavlović, G. Trajković, N. Videnović, A. Jovanović
01.01.2008.
Professional reviews
INHIBINS INHIBINS - QUALITIES, QUALITIES, SIGNIFICANCE SIGNIFICANCE AND HIS ROLE IN PREGNANCY PREGNANCY
Inhibins are glycoprotein hormones of which there are two molecular forms, inhibin A and inhibin B. Classically, inhibin is known to have a negative feedback effect on pituitary follicle-stimulating hormone secretion. The fetoplacental unit produced inhibin throughout pregnancy. Inhibin Ais the predominant molecular form of inhibin in maternal circulation from 4 week of gestation. Although the precise biological function of inhibin Ain pregnancy is unclear, it is evident from recent studies that inhibin A could be a better marker of placental function than human chorionic gonadotropin because of its shorter half-life. The possible clinical application for the measurement of inhibin Ain early pregnancy could be in predicting miscarriage , Down's syndrome, preeclampsia and fetal growth restriction in the first and/or second trimester before the onset of yhe clinical symptoms. Inaddition, several evidences underline the potential role and the clinical usefulness of their measurements in the diagnosis, prevention,prognosis and follow-up of different gestational pathologies such as:threatened abortion, placental tumors, hypertensive disorders of pregnancy,intrautherine growth restriction,fetal hypoxia.The measurement of inhibin Aand activin Ainto the biological fluids of pregnancy will offer in the future further possibilities in early diagnosis,prediction and monitoring pregnancy diseases.
M. Vukotić, G. Trajković, M. Parlić, A. Ćorac, M. Mirković, N. Milošević
01.01.2008.
Case Reports
MIGRAINE COMBINED WITH ACM ANEURISM IN 15 YEARS OLD PATIENT CASE PRESENTATION
Migraine headaches are very frequent and its prevalence rates between 15-18% in women and 5-6% in men (1). Migraine attacks vary very mach in their intensity and frequency from patient to patient, and during the time in same patient. Even 75% of the patients describe attacks as heavy or extremely heavy. Although somatic and neurology exams between attacks reveal regular findings, migraine can have great impact on the patients quality of life (social limitations, complications caused by drugs, psychiatric and somatic morbidity (2) In spite usual believes headaches are very often in children. Before puberty boys safer more frequently than girls. Just the same, in early childhood as well as in adolescence migraine pain could mimic and compromise bringing up the right diagnosis of the other possible somatic causes, most likely one sided headaches. Our case presentation points out one of the possibilities. L.M 15-years old patient hospitalized on the pediatric department of the ,,Kralj Milutin Clinic,, in Laplje Selo on October 2007, under the diagnosis of blanking out and left sided headache. After neurology exam and neurology diagnostic procedures done MR cerebra and MR-angiography, diagnose of aneurism of right the ACM (arteria cerebra media) has been established, and operatively treated. After the intervention, patient stays without intensive headaches , only weak pain on the left side of the head, now and on, without blanks.
S. Čolić, Lj. Smiljić, M. Nenadović, G. Trajković, J. Marjanović
01.12.2008.
Original scientific paper
PSYCHOTICISM PSYCHOTICISM AS AN ETYOLOGICAL ETYOLOGICAL FACTOR OF POLITOXICOMANIA OXICOMANIA
The psychotropic drug addiction is steadily increasing in the subpopulation of the young generation. The objective of this paper is to investigate the degree of psychoticism as a disintegrating personality phenomenon. Psychoticism comprises elements of autism, insensitiveness, aggression, asocialisation. This irregularity in cognitive processes was tested on three groups of people: politoxicomaniacs, psychotic patients and a control group. The DELTA test reported convincingly raised dimensions on the scale of psychoticism: general executive functions (GEI), schyzotypical behaviour (SHD) , paranoia (P), and depression (D), as crucial factors not only for developing addiction but also for achieving long - term and stable abstinence. Apilot study retesting of abstinent persons, has confirmed, after a year's treatment, the change in their behaviour ( by improving all the results on DELTAscale of psychoticism).
R. Šapić, Ž. Krivokapić, M.N. Nenadović, G. Trajković
01.01.2007.
Professional paper
HEALTH STATE EVALUATION OF POPULATIONHISTORICAL LOOKING BACK AND MODERN APPROACH
Search for objective indicators of health state of the population is essential public health issue. First serious attempt of health evaluation of the population were observed in the end of 18. and beginning of the 19. century. In this period of time, description of health population was mostly based on indicators which were based on data of numbers of death. Later, because of significant decrease of infectious disease and improvement of life and work conditions comes to an extension of average life span. Also, comes to a change of conceptualization of health. As a result of all this changes it has been noticed need for consideration of other aspects of health. As a outcome, indicators of disease, disability and non-biological indicators of health (as a approach to health service, quality of health protection, condition of living, life style factors and environment factors) are more and more necessary for documentation of human capacity for physical, mental and social functioning as a objective analysis of health state. To get all the information of all aspects of health which can not be get from health statistics routine data, was started with examination of population health trough interview, respectively polling out representative population sample. Aim of this studies is to get basic information about population health, in manner to supplement the picture of population states, identify health problems and health needs, to get the picture of representations of risk factors among population; to get the picture of health service utility; to find out health disparity among different countries and inside the country, among different population groups; to follow the change of health states during the time; to follow achievement in health strategy; to insure data for people which are creating health politics, in manner to coordinate theirs politics, strategy and programs. This kind of study is taking place every year in many countries and in others periodically. In our country this kind of studies were done during the year of 2000. and 2006
M. Mirković, M. Parlić, G. Trajković, A. Ćorac, M. Vukotić, S. Đurić
01.12.2007.
Original scientific paper
THE EFFECT OF PHYSICAL EXERCISE ON LIPID AND ELECTROLYTE LEVEL IN BLOOD SERUM OF ACTIVE SPORTSMEN AND SEDEMTERY PERSONS THE EFFECT OF PHYSICAL EXERCISE ON LIPID AND ELECTROLYTE LEVEL IN BLOOD SERUM OF ACTIVE SPORTSMEN AND SEDEMTERY PERSONS
Systematic and programmed physical exercise, called training, play a significant role in human health and ability improvement. A moderate physical exercise is considered as a very efficient method of increasing general physical ability and reaching the top results in sport, and simultaneously contributes to health quality of persons having sedentary professions. In active sportspersons, ability of cardiovascular, respiratory and bone-muscle systems are determined by training quality itself. Sportspersons show characteristically better adaptability of neurohumoral system to effort, as well as a higher activity of intracellular enzyme systems. Well-dosed physical exercise has an exceptional influence on human health, above all by regulating cholesterol blood level and electrolyte level of serum, whose minimal change can directly affect human health. This study was aimed to establish quantity and quality of organism response to physical exercise, in regard to level of daily training, by determining lipid fractions level in serum and electrolyte composition of serum. The study involved 50 healthy men in age between 20 and 25, divided into two groups. The first group was composed by physically untrained men, chosen by the random sample method. The other group of subjects was composed by 35 active sportsmen, chosen by direct selection for the best-trained ones among them. In order to reach a submaximal exertion, we used Astrand's test of submaximal exertion on the bicycle-ergometer. Blood samples were taken immediately before and after testing. The following parameters were determined in blood serum: high-density lipoproteins (HDL), low-density lipoproteins (LDL), triglyceride + + 2+ 2+ - content, as well as concentration of sodium (Na ), potassium (K ), calcium (Ca ), magnesium (Mg ) and chlorine (Cl) ions. On the base of our research we concluded that physical exercise of submaximal intensity did not lead to any quantitative and qualitative change of lipid fractions in blood serum of untrained persons. Physically inactive persons had higher serum concentrations of triglycerides and total cholesterol in regard to the investigated sportsmen. At the same time, sportsmen showed a higher HDL content of serum. Physical exertion in sportsmen led to a significant rise of triglycerides and highdensity lipoproteins content of serum, and the levels of total cholesterol and low-density lipoproteins did not changed + ++ significantly. Physical exertion of submaximal intensity in both studied groups caused a significant increase of Na , Ca and ++ + - Mg ion concentration, while concentration of K and Cl ions did not changed significantly. Numerous clinical studies showed that moderate aerobe exercise amplifies endothelial function and reduces cardiovascular risk
S. Smiljić, D. Radović, Z. Milanović, V. Nestorović, M. Miletić, G. Trajković, D. Mirić, S. Dragić, B. Biševac
01.01.2006.
Original scientific paper
SYMPTOMS, SIGNS AND ABNORMAL CLINICALAND LABORATORY FINDINGS IN WORKERS IN THE CHLORINE-ALKALI ELECTROLYZE
Elementary mercury using as cathode in process chlorine-alkali electrolyze. Mercury vapor makes in process going in work setting atmosphere. Aim of the work is to examine whether symptoms, signs and abnormal clinical and laboratory findings are in the correlation with work in the chlorine-alkali electrolyze. Examination of air pollution work setting discovers that the major factor of air pollution is mercury vapor. On periodical view at 2000, 2002 and 2004 year was examine 571 respondent, and their diagnosis was entered in report, from which was separated symptoms, signs and abnormal clinical and laboratory findings. Workers on different workplaces are exposes in different degrees. Examinees were divided in a four group according to the grade of exposure: I group day by day exposed; II group sporadically exposed; III group earlier exposed; IV group not exposed. I, II and III group are workers which work in the process chlorine-alkali electrolyze. IV group was control group and her compose administration personal. The statistical testing differences of frequency between groups according to the grade of exposure is showed there is statistical significantly difference between I and III, and II and IV groups. We are concludes that symptoms, signs and abnormal clinical and laboratory findings, statistically significantly, there is in persons which are permanently and long term worked in the chlorine-alkali electrolyze setting, from persons which are not permanently expose or nonexpose
A. Ćorac, G. Trajković, M. Mirković, P. Kuzmanović, M. Vukotić, S. Samardžić, V. Mišolić
01.01.2005.
Original scientific paper
MERCURY VAPOR AIRPOLUTION AND THE XI th GROUP OF DISEASES BY ICD - 10 REVISION
In process of chlorine-alkali electrolyze the big mercury failure exist in vapor shape, which across respiratory system, expire in exposed persons organism. The aim of the work was to examine connection between mercury vapor air pollution and sicknesses coming from diseases belonging to the XI group of diseases by International Classification of Diseases th (ICD) - 10 revision. Exploring groups were workers “Kalium chemistry” factory and administration at CI ”Zupa”. Recognized diagnosis on periodical exams year 2000, 2002 and 2004 were entered in reports (expertises) analyzed later on. Analyzed reports for total 571 examinees were done, 184 examinees year 2000, 191 examinees year 2002 and 196 year 2004. As of diagnosis recognized the diagnoses were separate for diseases belonging to XI ICD group. Examinees were divided in a four group according to the grade of exposure: I group day by day exposed; II group sporadically exposed; III group earlier
exposed; IV group not exposed. First, second and third group of examinees were workers of “Kalium chemistry” factory. It was established during the examination at rooms were exposed workers stay that only mercury vapor pollution 3.01 overcomes Maximum Permitted Concentration allowed by JUS. The frequency differences testing between groups according to the grade of exposure, like as frequency differences testing of sicknesses between all exposed opposite un-exposed, showed
to us that differences are statistically significant. Based on the results of the this research it can be conclude that connection exist between mercury vapor air pollution and sicknesses coming from diseases belonging to the XI group of diseases by ICD.
A. Ćorac, G. Trajković, S. Samardžić, A. Milovanović, J. Lekić