The aim of our work was to inquire characteristics of myocardial infarction in diabetic patients.We questioned
prospectively 441 patients, diagnosed with acute myocardial infarction. Diabetes mellitus (DM) was found in 31,3%
patients. Atrial fibrillation was found in 16,7% patients with DM and 7,3% on patients without DM(p<0,05).Ventricular
arrhythmias gr.III was found in 18,8% patients with DM and 15,8% on patients without DM (p>0,05), gr. IV 24,6% vs.
12,9% (p<0,05) and gr.V 18,1% vs.9,9% (p<0,05). Heart failure (NYHA I) was found in 10,9% patients with DM and
10,6% on patients without DM (p>0,05), heart failure NYHA II 13,8 vs.10,6% (p>0,05), heart failure NYHA III 14,5% vs.
5,6% (p<0,05) and heart failure NYHAIV 10,1 vs. 3,3% (p<0,05).Cardiogenic shock was found in 21,7% patients with DM
and 10,2% on patients without DM (p<0,05). QRS scor was found 8,3+-2,9 in patients with DM and 4,5+-1,5 on patients
without DM (p<0,05). In-hospital mortality was found 20,3% in patients with DM and 8,2% on patients without DM
(p<0,05). Post-hospital mortality was found 10,2% in patients wuth DM and 5,1% on patients without DM (p>0,05).
Myocardial infarction in patients with DM have difficulty clinical flow and higher mortality

Very important role in the forensic investigation of mass graves takes forensic anthropology. Anthropologists take
part during the exhumation and later through the investigation and identification procedures. Forensic investigations of
mass graves in Kosovo and Metohija are going on. In this paper we observe all cases that were exhumed and identified during 2001., 2002., 2003. till the 1. 05 2004. In this time 280 dead bodies were exhumed and forensic team did autopsies, but
111 dead bodies were identified. Our aim was to analyze anthropological measurments (gender, age and stature) and compare them with the real state on identified dead bodies. Scientifics all over the world made the record of the very good results
of anthropology work. After our investigation we can say that anthropology is very valuable during the exhumation of mass
graves.

Penetrating injuries of the eye are an important cause of unilateral visual loss. Hemophthalmos is frequently and
serious complication in penetrating eye injuries. We studied a series of 422 cause, children aged 1-15 years, treated from
1989 through 1998. There were 324 (76.78%) boys and 98 (23.22%) girls in the study group, with a mean age of 8 years 4
monats. Complication from penetrating eye injuries with hemophthalmos is noticed in 62 cases (14.69%). 

Luteal phase defect is disorder of low progesterone secretion (low level), or very short luteal phase (shorter than 11 days). Consequence of that is late endometrium maturation, almost 2 days. Such endometrum impedes and makes impossible ovum nidation. Today we have luteal phase defect in 14% of infertility women, and in 21% of women of unknown infertility reason. This has been frequently seen in women with spontaneous abortion and hyperprolaktinemia. Diagnostic methods of DLF are biopsy of endometrium and measuring of progesterone level. The aim of this study is the examine endometrium maturation disorders. The study includes 30 women that are hospitalized in Clinical of Gynecology Pristina. Unknown reason of infertility and normal hormonal status had been in 13 (43%), and hyperprolaktinemia in 7 (56,7%) of women. Histological verificated ovulation had been finding out in 60%of women. Late endometrium maturation, luteal phase defect, had been verificated in 23,3% of women, from there in 29,4% of hyperprolaktinemic women and in 5,4% of women of unknown infertility reason. There was evidence of late endometrium maturation of 2 days (85,7%). and of 4 days th (5,4%). Progesterone level in DFLthe 20th day was 30 nmol/l, the 24 day of menstrual cycle was 28,8 nmol/l. Progesterone level in women with histological proved regular endometrium maturation was higher and it was 45, nmol/l. The lowest progesterone level that can be find in good functioning of luteal body was 31,8 nmol/l.Citohormonal findings in DFL was showing progesterone domination. Take a look at infertility and ovarian function must not be concern only on ovulation, it must take care of endometrium maturation.

Most fistula-in-ano arise as result of chronic infection of an intersphincteric anal glands and persistence may be related more to non-specific epitelisation of the track. Preoperative definition of the anatomy of the fistulous track and the internal opening plays a primary role in adequate planing of the operative approach to minimize iatrogenic damage of sphincters and fistula recurrence. The diagnosis of anal fistula generally is straightforward and is based on clinical features. By
using palpation of the perianal area, digital examination, and careful probing of the track, the fistula anatomy was defined.
Fistulography, radiografic evaluation, is not routinely indicated in the initial avaluation of fistulas but may be helpful in identyng an occult cause of recurrent or multiple fistulas or if examination is suggestive of inflammatory bowel disease. AIM:
is evaluation of importance of the fistulography for surgical treatment of the fistula-in-ano. The study is prospective. In includes 60 patients divided in two groupies, each 30 patients. Examined group was operated after clinical findings by using
careful probing of the track and fistulography. Control group was operated after clinical findings by using careful probing of the track. In patients, examined group, treated with fistulography allowed a corect diagnosis of primary track 43.3%, secondary track 40.0%, horseshoe track 50.0% and internal opening in 40.0% of patients. The clinical findings, in the same group patients, allowed diagnosis of primary track 76.6%, secondary track 60.0%, horseshoe track 100% and internal opening in 73.3% of patients. Preoperative definition of fistulous track and internal opening by physical examination and its relationship with anal sphincters are important factors influencing the results of surgical management. We do not recommend routine fistulography in the diagnosis of fistula-in-ano. 

In process of chlorine-alkali electrolyze the big mercury failure exist in vapor shape, which across respiratory system, expire in exposed persons organism. The aim of the work was to examine connection between mercury vapor air pollution and sicknesses coming from diseases belonging to the XI group of diseases by International Classification of Diseases th (ICD) - 10 revision. Exploring groups were workers “Kalium chemistry” factory and administration at CI ”Zupa”. Recognized diagnosis on periodical exams year 2000, 2002 and 2004 were entered in reports (expertises) analyzed later on. Analyzed reports for total 571 examinees were done, 184 examinees year 2000, 191 examinees year 2002 and 196 year 2004. As of diagnosis recognized the diagnoses were separate for diseases belonging to XI ICD group. Examinees were divided in a four group according to the grade of exposure: I group day by day exposed; II group sporadically exposed; III group earlier
exposed; IV group not exposed. First, second and third group of examinees were workers of “Kalium chemistry” factory. It was established during the examination at rooms were exposed workers stay that only mercury vapor pollution 3.01 overcomes Maximum Permitted Concentration allowed by JUS. The frequency differences testing between groups according to the grade of exposure, like as frequency differences testing of sicknesses between all exposed opposite un-exposed, showed
to us that differences are statistically significant. Based on the results of the this research it can be conclude that connection exist between mercury vapor air pollution and sicknesses coming from diseases belonging to the XI group of diseases by ICD.

Gonarthrosis is the most frequent artropathy of knee.The second joint of frequency and localisation osteorthrosis after joint of haunch. In complexive therapy of gonarthrosis, exept the medical therapy, important place has physical therapy
or special laser-therapy. 78 patients, where tested with a primary and secondary gonarthrosis, 19 men, and 59 women. They were all hospitalised on Rheumatology department of Internal Clinic of Clinical and Hospital Centre in Pri{tina. By objective using of parameters we show that, laser is a very important modern expedient on clinical results for gonarthrosis (volume of joint, volume of movements, muscle strength, and on the first pain, pain in static positions, pain in moving and night pain). It is seen that all values got by laserotherapy are statistically high significiant. During the use, of laserotherapy, the medical therapy was included.

Natural system of disease genesis is a complex occurrence. «Net» review of cause can be based on systematic approach and it doesn't have to, and so those are homonyms. Complex occurrence of the genesis of a disease is given as a arranged set by relation «predecessor-follower». Chain reaction is that one which has hierarchic arrangement because of managing. By systematic approach the causality is being created.

Change in left ventricular volumes, particularly end-systolic volume index is a major representative of left ventri cular dilatation, and is a predictor of mortality after acute myocardial infarction of anterior localization. Several large-scale trials have demonstrated beneficial effectiveness of ACE inhibitors on the process of left ventricular remodeling after myo cardial infarction, not only in patients with compromised systolic function. Aim of the study was to evaluate the influence of therapy for ACE inhibitors in the early faze of anterior myocardial infarction, trough dynamics of left ventricular volume in dexes. During six months 30 patients were evaluated with echocardiography in admission, before leaving the hospital, after
three and six months after myocardial infarction. In evaluated group there was increased end-diastolic and end-systolic vo lume index, but without statistically significant value. There were no new cardiac decompensations. We concluded that ACE inhibitors given in the early stage of acute myocardial infarction anterior localization have beneficial effect on the process of left ventricular remodeling and that is recommended to bee given to this patients, after excluded contraindications

Biliary calculosis is the most frequent disease of the hepathrombial system. Inflammation of the gall bladder appears in the acute and chronicle form. Acute inflammation presents one of the frequent complications of the gall bladder
calculosis. Acute inflammation of the gall bladder can appear in catarrhal, phlegmonous, gangrenous perforative form. Perforation of the inflamed changed gall bladder can lead to the diffuse biliary peritonitis, pericholecystitis and formation of
pericholecystitis infiltrate or abcess. Very often the acute inflammation of the gall bladder appears in combination with Acute inflammation of the pancreas. For the production of the work the biyearly material of the Emergency Surgical Centre
“Simonida” in Gračanica is used. In the ESC Simonida, in the period from January to December of 2004, 375 patients were operated. In the same period of time we operated 52 (13.86%) patients because of the gall bladder disease and biliary ways.
There were 45 female patients and 7 male ones. Gall bladder disease is 6.5 times more frequent at females in our material. Hard security situation and limited freedom of movement are one of the most important reasons of patients' late report to the
doctor, and appearance of the heavy forms of the inflammation of the gall bladder and biliary ways. The acute form of the inflammation of the gall bladder was noticed at 25 patients. The complications of the disease in the sense of cholecystopancreatitis, choledolithiasis, suppurating cholangiitis, choledolithiasis i cholecystoduodenal fistule were found at 27 patients. Postoperative complications were verified at 3 patients, wound infection at 2 patients and peritonitis at one
patient after drawing ouf the T-drain.

Defined daily dose (DDD) is arbitrary chosen technical unit for measuring medicament usage and it is not a recommended therapeutic dose. It is in fact a statistical parameter for monitoring medicaments usage, and it is related to the
dose which is usually prescribed for the indication that the medicament was registered for. The aim of this work is to perform a detailed analysis of the extent and structure of the region of South Backa. According to the obteined data, medicaments
used in treatment of gastroinestinal tract contributed with 15.52 DDD/1000 inhabitants per day. Most commonly used are antacids and anti-ulcer drugs (8.14 DDD/1000 inhabitants per day). Medicaments used in treatment of muscular and skeletal
system contributed with 14.30 DDD/1000 inhabitants per day. Antiinflammatory and antirheumatic drugs sre used in amounts of 14.18 DDD/1000 inhabitants per day. In our country there is no complex survey of drug usage because there is no way of monitor ing which could apprehend all possible information sources. Defined daily dose is not introduced into practical qualitative and quantitative monitoring. It is necessary to make systematic network of information sources to provide for insight into medicament usage

The retrospective study included all patients treated at Clinical Centre in Kragujevac, who needed an acute HD treatment due to vital endangerment, during 2003. The objective of this study was to demonstrate our experiences in treating these patients using central venous catheter. The results of this study show that femoral catheters are dominant (over 95%), with slight using of jugular and subclavial catheters (5%), in spite of the recommendation of the American Association for Renal Diseases to use femoral catheters only for patients supposed to be in hospital during the interval of 5 days. The
frequency of infections in our study (16,6%), coincides with the data of the American Association for Nosocomial Infections (NNIS)[1] (17,8% catheter infections). Gram-positive bacterium from Staphylococci group are the most frequent cause of catheter infections also in our patients

The urgent surgical intervention need great atention in pregnant patients because of vital indication all surgical procedure interffer with pregnancy togheter with general anaesthesia and could cause complication of pregnancy and some times a damage of the foetus. Our study include all surgical procedure as the acute abdomen, trauma and politrauma in pregnant patient. Our aime was to give general anaesthesia which should be safe for mother and foetus.Post-operaative therapy and treatment of patients was done by theam of anaesthesia and gynecologists. The anaesthesia monitoring and surgical procedure have been improved up to the presset day but there are steel present great ricks in a treatment of this type of patients.The criteri in surgical and conservative treatment of pregnant patients was determined in colsultacion anaestetist-gynecologists.

Fibromyalgia presents a great clinical problem. Existence of no objective criteria for diagnosis is the key problem of this disease in the clinical rheumatology. The task of this work was to present the most practical quantification of fibromyalgia in every-day practice. Out of 37 patients there were 29 (78,3%) women, and 8 (21,6%) men. Out of this number there were 3 (8,1%) with primary fibromyalgia, 8 (21,6%) with secondary fibromyalgia, 25 (67,5%) were concomitant, whereas there was only one atypical case, i.e. (2,7%).

The Global Initiative for Chronic Obstructive Lung Disease (GOLD) has emerged due to joint efforts and support of the American National Heart, Lung & Blood Institute and the World health Organisation, with the objective of enlightening the major issues regarding COPD, and reducing the morbidity and mortality rates of this disease. An exacerbation of respiratory symptoms requiring hospital treatment is a common clinical manifestation of COPD. The exacerbation is usually induced by an infection of the tracheobronchial tree or air pollution, but in about one third of severe exacerbations the cause remains obscure. Acute COPD exacerbations are effectively treated by the application of inhalatory bronchodilators (particularly β-agonists and/or anticholinergics), teophylline and systemic, especially oral glucocorticoids. The patients with COPD exacerbation presented with the clinical symptoms of a respiratory infection (e.g. increased volume and altered colour of the sputum and/or fever) may benefit from antibiotic treatment. Non-invasive Positive Pressure Ventilation (NPPV) in acute exacerbations may improve blood gases and pH levels, reduce intrahospital mortality and the need for applying invasive mechanical ventilation and intubation, shortening thus the hospital treatment duration

The surface area of the small intestine is enhanced by three morphologic features that are peculiar to the gut: plicae circulares, the villi and the microvilli. The plicae circulares (circular folds) consist of mucosal/submucosal invaginations that are predominantly located in the duodenum and jejunum. These infoldings are visible on gross inspection. The intestinal villi, finger-like projections that protrude into the intestinal lumen, are approximately 0,5-1,5 mm long and cover the mucosal surface. They can be viewed by close inspection of the mucosa under low-power microscopy. Their microscopic appearance varies: duodenal villi are characteristically broad and leaf-shaped, jejunal villi are tall and thin, and ileal villi are short and broad. The length and shape of the villi also vary with geographic region. At the base of the villi, the epithelium enters the lamina propria and forms the crypts of Lieberkühn, which extend almost to the muscularis mucosae. The microvilli are sub-light microscopic tubular projections that are extensions of the apical cell membrane and compose the brush border. There are the enzymes and receptors in these structures which are required for terminal digestion and absorption

Most frequent congenital malformations in human are congenital heart disease (30%). In this article we represented basic of their etiology, pathogenesis, diagnostic and new therapeutics possibilities. Also we represented three cases of congenital heart disease. These cases we considered as very interesting. First of all, in this article we try to emphasize some aspects of this problem, which is not well known, especially in our environment. This very rare congenital heart disease shows how much diagnostic procedure can be difficult and treatment hard or impossible besides big improvement, which has be done last decades. We must learn much more about congenital heart disease!

We want to present a boy with a several different, but benign disorders. Keratosis pilaris and strophulus infantum are very frequent, esspeciallv in children. Its association is not important. Pseudoacanthosis nigricans is especially associated with obesitas, and then this disorders is benign

Injuries of genital organs caused by electricity are rarely isolated and they begin with injuries of the other parts of a body. We present you a patient with very rare and difficult genital organs injury which brought to a very severe damage and lasting invalidity. The genitals were being carbonized but a patient have to spend the rest of his life with a final perineostomy.

Considering the fact that there are freer and more varying sex activities, we have today more varying genital organs injuries both at men and women. We present you a patient with two penis injuries caused by a bite. It must be done a complete wound treatment with ATprotection and maximum antibiotics appliance. It is necessary to perform an AIDS test.

The authors present you two cases of luxatio testis. Luxatio testis is a very rare injury caused by the influence of some strong force or blow. Testicle is luxated in ingvinal chanal, perineum, subcutanue penis tissue and rarely abdomen. Conservative surgical treatment always have to be done

.
Diabetes mellitis,type 2 is often associate with disorders metabolism of lipid. That is base for development athero sclerosis, coronare disease and peripheral vascular complications. Patient with diabetes earlier get cariovascular disease. Frequency in equllent in female and male sex. Atherosclerosis is proces which is started earlier in patiens with diabetic, than in healthy population. So, prevention of cardiovascular disease is very important. When we elimination risk factors: smoking, hypertension and lipids, we will reduce coronary syndrome.The clinicly studies show us that the statins drugs are choice for prevention and controle metabolism lipids in these pations. Statins drugs had been show us the best therapy the efects on evolution of atherosclerosis plaques, reversed endothel disfunction and modulation of thrombotic parametars