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Volume 52, Issue 1, 2023

Online ISSN: 2560-3310

ISSN: 0350-8773

Volume 52 , Issue 1, (2023)

Published: 01.11.2024.

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01.01.2003.

Professional paper

COMPARATIVELY ANALISYS STRUCTURE OF CONGENITAL MALFORMATIONS FOUND ON THE FETUSES AND NEWBORNS AUTOPSIED IN 1991 AND 2001

The research was conducted at the Department of Pathology and Histology of Clinical center of Novi Sad. We analysed the reports of autopsies of newborns (to 28 days old), stillborns and miscarried fetuses in 1991 and 2001. Found
malformations were classified according to organ systems. Results for 1991 show next structure of congenital malformations: 3 malformations of central nervous system (14.29%), 0 malformations of urogenital system (0%), 3 malformations of
gastrointestinal system (14.29%), 1 malformations of musculosceletal system (4.76%), 9 malformations of cardiovascular
system (42.86%), 1 chromosomal defects (4.76%), 4 multiple malformations (19.05%). Results for 2001 have next value: 9
malformations of central nervous system (27.27%), 4 malformations of urogenital system (12.12%), 5 malformations of
gastrointestinal system (15.15%), 0 malformations of musculosceletal system (0%), 4 malformations of cardiovascular
system (12.12%), 2 chromosomal defects (6.06%), 9 multiple malformations (27.27%). By the comperison of the results of
structure of congenital malformations in 1991 and 2001, we can conclude that the differences of cardiovascular and urogenital malformations are statistically important

M. Erić, M. Misolić, V. Pilija

01.01.2002.

Original scientific paper

ACTIVATES OF GLUTATION PEROXIDASE, GLUTATHION AND GLUTATION REDUCTASE IN HEALTHY AND DIABETES (INSULINE DEPENDENT) PATIENTS

Reduced glutathion (GSH), glutathion-reductase (GR) and glutathion-peroxidase (GSH-Px) are significant indicators of oxidative stress. Oxidative stress is a consequence of increased production of reactive oxygen radicals and/or on the other hand, insufficient antioxidative protection. It is well-known that free radicals have key role in the large number of biological phenomena, such as differentiation, transformation, signal transduction, aging etc., and they are important factors in pathogenesis of various diseases (carcinoma, diabetes, Alzheimer, Parkinson, aterosclerosis). This paper presents results of investigation of content of GSH and activities of GR and GSH-Px in healthy patients and diabetes insulindependent patients between 20 and 75 years of age in the region of Indjija. Correlation between investigated parameters in healthy persons and diabetics was found, as well as with results of similar investigations in other countries. Investigated sample comprised 200 healthy patients (20-75 years) divided into 5 groups, and 80 diabetes patients divided into 4 groups. Every group consisted of equal number of males and females. Above mentioned parameters were determined in hemolysate. Parameters change depending on patient age, and changes are more intense in all patients. Some differences exist in correlation of our results with results obtained in other regions.

А. Kozić, М. Popović, V. Ivetić, V. Pilija

01.01.2002.

Case Reports

SMELL DISORDER IN PATIENT AFTER INFLUENZA

Hiposmia or anosmia are common cases after infections. The virus of influenza is most common cause of anosmia
and hiposmia. In a cause of hiposmia and anosmia which are the results of influenza it is need to start with regular and actual theraphy, or in other case anosmia or hiposmia are permanent.

S. Savović, V. Ivetić, V. Pilija, S. Lemajić, V. Kljajić, M. Buljčik

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