In this research it was examined how fatigue in the working process affected the speed of reaction on a complicated
stimulus, and also on the frequency of inadequate reactions. The investigation was carried out by means method of combine
reaction time (CRT). CRT is the shortest time that passes from the moment when a person is affected by a complicated stimulus until the moment when the person responds to the stimulus, by making adequate and complicated reaction. CRTwas registrated in working population of railroad employees who were divided in two groups:group of locomotive drivers (n= 44) and group of a railroad employees (n=25). In the group of locomotive drivers it was taken into the consideration whether the type of locomotive was electrical or diesel power. In both groups, CRT was registrated in two phases of working process; before and after daily work. Results showed that in both examined groups CRT got significantly extended after the
working process. Duration of CRT was longer before and after working process in the group of electrical power locomotive
drivers compared to diesel power locomotive drivers. Fatigue did not affect significantly on the frequency of incorrect answers

Planning daily activities, depending on neurophysiological chronotipology, is one of the steps, which should be taken towards the more successful, healthier, high quality life. Aperiod of time within a day during which the individuals of both sexes, different age and profession are intellectually the most optimally efficient, was determined in the paper. The chronotype of a given person was taken into account for that purpose. The research was carried out using a questionnaire. The questioned individuals were divided into four groups: 120 students at the University of Novi Sad, 50 professors at the University of Novi Sad, 50 railway workers and 50 female civil servants employed in administration. The obtained results show the following: the highest percentages of students belong to the morning chronotype. They sleep more than professors do and the optimal time convenient for mental and heavy physical work is from 11 AM to 1 PM. This data should be taken into account while planning student tests. The University professors, both male and female, belong to the morning chronotype. The female professors sleep more than male professors, but are psychologically and physically optimally productive at the same time as the male professors, from 8 AM till 10 AM. In the group of railway workers, the most common are individuals of indifferent chronotype. The highest percentage of women employed in administration belong to the morning chronotype and for their optimal psychological activity they choose the period of time between 8 and 10 AM, as well as the railway workers. According to the opinion of most people that have been questioned, among all of the abovementioned groups, the optimal five-hour working period should begin at 8.30 AM.

Reduced glutathion (GSH), glutathion-reductase (GR) and glutathion-peroxidase (GSH-Px) are significant indicators of oxidative stress. Oxidative stress is a consequence of increased production of reactive oxygen radicals and/or on the other hand, insufficient antioxidative protection. It is well-known that free radicals have key role in the large number of biological phenomena, such as differentiation, transformation, signal transduction, aging etc., and they are important factors in pathogenesis of various diseases (carcinoma, diabetes, Alzheimer, Parkinson, aterosclerosis). This paper presents results of investigation of content of GSH and activities of GR and GSH-Px in healthy patients and diabetes insulindependent patients between 20 and 75 years of age in the region of Indjija. Correlation between investigated parameters in healthy persons and diabetics was found, as well as with results of similar investigations in other countries. Investigated sample comprised 200 healthy patients (20-75 years) divided into 5 groups, and 80 diabetes patients divided into 4 groups. Every group consisted of equal number of males and females. Above mentioned parameters were determined in hemolysate. Parameters change depending on patient age, and changes are more intense in all patients. Some differences exist in correlation of our results with results obtained in other regions.

Hiposmia or anosmia are common cases after infections. The virus of influenza is most common cause of anosmia
and hiposmia. In a cause of hiposmia and anosmia which are the results of influenza it is need to start with regular and actual theraphy, or in other case anosmia or hiposmia are permanent.