In our work we analyzed utilisation of antibiotics for systemic use at the Surgical Clinic of the Clinical Hospital Centre - Pristina in Gracanica in 2007. and 2008. Data on antibiotic utilization were delivered on the basis of drug dispensing records from the Central Hospital Pharmacy during the two-years period. Antibiotics were distributed inside the ATC/DDD system in accordance with WHO guidelines. Quantitative antibiotics' utilisation was expressed as number of defined daily doses per 100 patient-days (DDDs/100 PD). Overall use of antibiotics in 2007 was 123.37 DDDs/100 PD, and 125.09 DDDs /100 PD in 2008. Three most utilized antibiotics in 2007. were cefuroxime 24.26 DDDs/100 PD (19.66 % of total antibiotics' use), ceftriaxone 16.65 DDDs/100 PD (13.49 %), and cephalexin 15.78 DDDs/100 PD (12.79 %). In 2008. the most utilized were ceftriaxone 23.23 DDDs/100 PD (18.57 %), cefuroxime 22.53 DDDs/100 PD (18.01 %), and co-trimoxazole 19,55 DDDs/100 PD (15.63 %). Qualitative and quantitative part of the consumed antibiotics was mainly in accordance with the results of similar researches in our country.

Hypokaliaemia can be cause for beginning cardiac arrhythmias in patients with acute myocardial infarction. The aim of this investigation is to determine correlation between kalium level in serum and cardiac arrhythmias and conveying, to note down in first 24 hours in patients with acute myocardial infarction (AMI). Patients in this study attended in department of Internal medicine(coronary department ) in hospital in Health center in Kosovska Mitrovica.In this prospective study for one years we analyzed 110 patients with diagnosis of acute myocardial infarction. We found that cardiac arrhythmias represented in the most noumber of patients in the first 24 hours from receiving in hospital- 83,63%.The patients have had the more noumber of complex VES(20,91%),SVT(18,18%) than other cardiac arrhythmias in the first 24 hours from their received in the hospital. The low level of kalium have note down in 9,09% patients. The comlex VES have represented in patients with low level of kalium as VF. In the presence of kalium level under the 4,0 the risk for ventricular arrhythmias is higher.SVT have had in 20% patients with acute myocardial infarction,SVB in 10%,SVES in 16%,VF in 7% patients with normal kalium level in serum as branch block and AV-block I, II, III degree. Hypokaliaemia have influence on represence of VES and VF, but have not influence on represence of supraventricular arrhythmias and the disorders of conveying.

The clinical and metabolic anomalies observed in patients with type 2 diabetes are associated with high risk of cardiovascular disease (particulary coronary heart disease), witch is responsible for 75% of all death in diabetic patients. Diabetic people have cardiovascular risk factors comparable to those of nondiabetics who have had myocardial infarction or stroke. To determine main risk factors for coronary heart desease (CHD) and differentes among diabetics we analyzed 86 patients.Patients in this study attended in Institute of endocrynology,diabetes and matabolic disorders in Belgrade. The diagnosis was based on typical clinical manifestation: high levels of glucose (higher than 6,1mmol/l), high cholesterol and tryglicerides, hypertension and overweight. In the control group we have had 20 adult, healty people without metabolic disorders. We found that diabetics with coronary heart disease have had the higest level of glucose (13,2mmol/l), cholesterol (6,96mmol/l),tryglicerides (2,84mmol/l). Arterial hypertension in the group of diabetic patientes with CHD have had 72,7 %, or 40 patients of 55 patients of whole group. Type 2 diabetes and hypertension share certain risk factors such as overweight, visceral obesity,and possibly insulin resistence. This study strenthgenes the hypothesis that cholesterol and the arterial hypertension have central role in develpoment of CHD, but in non-insulin depended diabetics they associated with metabolic disorders witch play an important role in increasing the risk of coronary heart disease.