The origin of ophthalmic artery (OA) and surrounding structures was investigated in 25 cadavers by three different methods: macroscopic, stereomicroscopic, and histological observations. The following results were obtained. In 42% of the specimens the origin of the OAwas observable in the cranial cavity and defined as the intradural type, running alongside the optic nerve within the subarachnoid space. The other 58% were named the extradural type of the OA, originated within the cavernous wall or cavity, and entered directly the optic dural sheath, thus no part of the OA was visible in the cranial cavity. OApassed through the optic canal within the dural sheath of the optic nerve. In 44% of our specimens the OAwas on the inferomedial side of the optic nerve at the entrance point to the optic canal. OAleft the optic canal at its lateral border in the apex of the orbit in 72% of our specimens. For descriptive purposes the intraorbital course of the ophthalmic artery has been divided into three parts. The first part usually runs along the infero lateral aspect of the optic nerve. The second part crosses over (in 88%) or under the optic nerve running in a medial direction. The third part extends medially to its termination. These anatomical data may provide important information for understanding the variety of the pathology in this region and is also useful for designing operative strategies.

Artrosis as degenerative rheumatic discase of joints, which is the most often with older people, and if it is not cured adequotety it brings to the serious defects. The air of warr is to evaluate functional condition of people sick of hip osteoarthrosis by using two standardised questionnaires for the hip osteoarthrosis. Material and methods: The examination included 100 patients with hip osteoarthrosis (73 women and 23 men) whase diagnosis was set on the basis of ACR criteria. The result : In the group of 100 patients (73 women and 27 men) with average old of 58,87 years and average lasting of sickness 8,28 years from which 77 had bilateral representation of hip osteoarthrosis and 23 unilateral representation of hip osteoarthrosis showed these results of funcional tests: a) averagevalne of Womac score is 50,18 (min 13,00 max 77,00) that is in the medium category of funcional disableness, b) average volne of Lequesne score is 14,12 (min 4,00 max 23,40) that shows high degrece of functional of functional disableness. Both questionnaires are mutvally correlated with a higs degree of statistic importance in the whale score (r= 0,454; p< 0,0001) and so in the subsections: pain (r= 0,540; p<0,0001) and physical functional scale r= 0,728; p< 0,0001). The intensity of pain also correlated with time of step and Womac score (r= 0,454; p< 0,0001), and with the lasting of sickness, female sex, and there wasnt statisticaly important coreelation with Lequesne score (r= 0,215; p= 0,08). Radiologic findig correlated with reduction of the moveness amplitudes, the time of step, the lasting of sickness, the of the patient, Womac score (p< 0,05), and it isnt correlated with Lequesne score. The reduction of the moveness of amplitudes is the hips correlated with radiographic presentation, the time of step, Womac and Lequesne score, localization, the age of patients and using of help materials. Conculsion: The valne of both indexes correlate with the usual clinical indications of coxarthrosis progression, and Womac index shows better correlation with radiologic progression of sickness than with Lequesne index.

Leptin was discovered in 1994, finding, that marked the beginning of a new understanding about white adipose tissue. Up to end of 20th century this tissue was viewed as an inert tissue, devoted to body protection from heat loss and to passively store energy. This static vision, changed with identification of the product of the gene obese (ob) wich accentuated the role of adipose tissue in the physiopathology of obesity-linked diseases, and led to the discovery of various adipokines, many of a pro-inflammatory nature. With emerged knowledge of (WAT)-derived adipokines, it is obvious that they can be now considered as the bond between obesity-related environmental causes, such as nutrition and lifestyle, and the biochemical shifts that lead to metabolic syndrome, inflammatory and/or autoimmune conditions, and rheumatic diseases. This paper deals with reviews of recent adipokine research, with particular emphasis to the role of leptin, adiponectin, resistin, and visfatin in chondrocyte function and skeleton, as well as in inflammatory and degenerative cartilage joint diseases.