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Volume 53, Issue 4, 2025

Online ISSN: 2560-3310

ISSN: 0350-8773

Volume 53 , Issue 4, (2025)

Published: 30.06.2025.

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01.12.2010.

Original scientific paper

THE INFLUENCE OF DOMINANCE OF A HAND WHEN PERFORMING THE ODDBALL TASK ON EVENT-RELATED POTENTIAL P300

Event-related potential which represents a large positive wave which varies in amplitude and depends on subject's capability as well as on stimulus modality on which subject needs to react and appears around 300 ms after stimulation is called event related potential P300. In 1965. Sutton and the assistants were the first to suggest division of evocated potentials, according to the stimulus that provoke them, on "exogenous" (under the influence of exogenous stimulus) and "endogenous" or "cognitive" provoked by endogenous stimulus, which depends on the state of consciousness (vigilance), attention, concentration and especially, the type of the task a subject needs to perform during the recording. One of the most studied responses of the event-related potentials is so called "P300", the late positive wave complex which appears around 300 500ms after the stimulus. It is gained when the subjects' attention is focused on the signal which rarely appears, especially if the signal has some emotional or motivational meaning. The aim of this work was to determine whether there was a difference in latency and amplitude of the event related potential P300 when the button is pushed with dominant hand compared with nondominant hand in both males and females. The experiment included 30 subjects (15 males and 15 females). P300 potential was provoked with the auditive "oddball" paradigm. Event-related potencial P300 is recorded with 10-20 system. Cz electrode is set in the middle of nazion-inion line, while Fz electrode is set on the third of nazion-inion line above frontal lobe. In classical "oddball" paradigm, when a subject reacted on the signal by pushing the button with dominant hand, the value of Fz end Cz latency was significantly shorter in comparison to the values of Fz end Cz latency gained by pushing the button with non-dominant hand (left hand) in males, while such differences were not found in females. 

B. Biševac, V. Ivetić, Z. Milovanović, V. Nestorović, S. Smiljić, M. Mišolić, M. Miletić

01.12.2008.

Original scientific paper

FUNCTIONAL CONDITION INFLUENCE ON STUDENTS REACTION TIME

Nowdays, reaction time is most often used in data processing as a quantitative method and technique for information step and speed processing. The aim of this investigation was to examine everyday work pressure on reaction time nd among students. An examination included 30 students of 2 year of Medicine Faculty 15 males and 15 females. Audible and visual simple reaction time as well as choice reaction time for 2, 4 and 6 stimuli was used for reaction time measurement. Measurements were done three times a day. Achieved results acknowledge statistically significant improvement of reaction time at noon compared to reaction time in the morning in all samples except for visual simple reaction time for male students. For all kinds of stimuli, reaction time were significantly prolonged in the evening in both groups. Therefore, we have concluded that morning activities had positive impact on students functional condition but afternoon activities acted like an additional stress that altered students latent fatigue to clearly observable acute fatigue.

M. Mišolić, V. Ivetić, V. Nestorović, Z. Milanović, D. Radović, B. Biševac, M. Erić

01.01.2007.

Professional paper

PSYCHOLOGICALASSESSMENT IN SURGICALLY TREATED PATIENTS WITH LUMBAR RADICULOPATHY

High frequency of appearance and use of expensive diagnostic and therapeutic methods makes lumbar radiculopathy the most expensive benign disease. The aim of the study was evaluation of types psychological reactions in surgically treated patients with chronic lumbar radiculopathy. Matherial and methods: We examined 50 surgically treated patients who had low back pain. The patients were multidisciplinary examined and treated on Medical Rehabilitation Clinic in Novi Sad. The Minnesota Multiphasic Personal Inventory (MMPI) was used to determine the personality profiles. Patients were tested after rehabilitation treatment. Results of the exploring showed the normal profile of personality in 70 % of patients and pathological profile in 30 % ( hypochondria in 8, hysteria in 5 patients and depression in 2 patients). All groups showed improvement in functional limitation during the rehabilitation treatment. Severity and length of pain after rehabilitation treatment is bigger in the group of patients with pathological profile of personality (p<0,005). Psychological factors may play an important role in the onset, severity, exacerbation, or maintenance of this type of chronic pain. Screening surgically treated patients with chronic lumbar radiculopathy with MMPI may be effective in identifying psychopathology

S. Tomašević-Todorović, M. Mišolić-Dejanović

01.01.2005.

Original scientific paper

DYNAMIC OF LEFT VENTRICULAR VOLUME AFTER ACUTE MYOCARDIAL INFARCTION UNDER THERAPY WITH ACE INHIBITORS

Change in left ventricular volumes, particularly end-systolic volume index is a major representative of left ventri cular dilatation, and is a predictor of mortality after acute myocardial infarction of anterior localization. Several large-scale trials have demonstrated beneficial effectiveness of ACE inhibitors on the process of left ventricular remodeling after myo cardial infarction, not only in patients with compromised systolic function. Aim of the study was to evaluate the influence of therapy for ACE inhibitors in the early faze of anterior myocardial infarction, trough dynamics of left ventricular volume in dexes. During six months 30 patients were evaluated with echocardiography in admission, before leaving the hospital, after
three and six months after myocardial infarction. In evaluated group there was increased end-diastolic and end-systolic vo lume index, but without statistically significant value. There were no new cardiac decompensations. We concluded that ACE inhibitors given in the early stage of acute myocardial infarction anterior localization have beneficial effect on the process of left ventricular remodeling and that is recommended to bee given to this patients, after excluded contraindications

I. Ivanov, J. Dejanović, I. Čurić, J. Čikoš, M. Vindiš-Ješić, D. Živkov-Šaponja, D. Hostić, M. Mišolić

01.12.2004.

Professional paper

INFLUENCE OF EMOTIONAL DISORDERS ON THE RECOVERY OF PATIENTS AFTER THE STROKE

The patients after the stroke besides impaired motor functions,often have cognitive and emotional disorders which
can endanger the successful carrying out of the rehabilitation treatment. The objective of this study was to estimate the
functional capability and to determine the cognitive and emotional disorders of the patients after the stroke. The research has
ecompassed 40 patients after the stroke of specified age and gender structure, treated in the Clinic for Rehabilitation, of the
Clinical Center in Novi Sad. The data have benn gathered from the anamnesis, clinical and neurological check, test of the
activity in everyday life, the findings of the psychologist on the emotinal status, as well as from the available medical
documentation about the patient. The average values of the Barthel's index are increased for 14.86% after the rehabilitation
treatment. The results show a strong presence of the emotional disorders with 57.5% of the patients. The increased values of Barthel's index and Mini Mental test at the end of the treatment show the undoubtfull importance of the rehabilitation
treatment in the recovery of the patients. The emotional disorders cause the worse recovery of the patients.

S. Tomašević, D. Filipović, N. Naumović, M. Mišolić

01.01.2003.

Professional paper

COMPARATIVELY ANALISYS STRUCTURE OF CONGENITAL MALFORMATIONS FOUND ON THE FETUSES AND NEWBORNS AUTOPSIED IN 1991 AND 2001

The research was conducted at the Department of Pathology and Histology of Clinical center of Novi Sad. We analysed the reports of autopsies of newborns (to 28 days old), stillborns and miscarried fetuses in 1991 and 2001. Found
malformations were classified according to organ systems. Results for 1991 show next structure of congenital malformations: 3 malformations of central nervous system (14.29%), 0 malformations of urogenital system (0%), 3 malformations of
gastrointestinal system (14.29%), 1 malformations of musculosceletal system (4.76%), 9 malformations of cardiovascular
system (42.86%), 1 chromosomal defects (4.76%), 4 multiple malformations (19.05%). Results for 2001 have next value: 9
malformations of central nervous system (27.27%), 4 malformations of urogenital system (12.12%), 5 malformations of
gastrointestinal system (15.15%), 0 malformations of musculosceletal system (0%), 4 malformations of cardiovascular
system (12.12%), 2 chromosomal defects (6.06%), 9 multiple malformations (27.27%). By the comperison of the results of
structure of congenital malformations in 1991 and 2001, we can conclude that the differences of cardiovascular and urogenital malformations are statistically important

M. Erić, M. Misolić, V. Pilija

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