The aim of work was to find out whether multiparity led to increased morbidity and mortality of mothers multyparous. Special attention was paid to appearance of diseases among mothers, both those developed during pregnancy and immediately after delivery. Multiparity is especially characteristic of women of Albanian nationality. Thus it is obvious that there is a reverse proportion between multiparous women and level of education the higher level of education is the smaller is the number of previous deliveries. There is a significant difference in apsolute number of deliveries according to the place of living in favor of rural residence. Number of both EPH gestoses (Eclampsia, pre-eclampsia) and indications for Caesarian section is increasing with multiparity. Abruption of normaly inserted placenta is significantly more frequent among multiparous women. It is obvious that multiparous women more frequently have bleedings during third and forth delivery period. There were also a large number of hysterectomies during delivery (75). Death rate of women is significantly increasing with multiparity. Eclampsia is the cause of death among more than half of all women. Resuming all data the autor is pointing out that grand multiparity, giving birth to more than six children, is, mfom medical point of view, an increased risk both for a newborn and a pregnant woman. Perinatal motality and morbidity is increased and high risk during pregnancy, delivery and puerperium is simultaneously rising until the pregnant woman's life is seriously endangered

Luteal phase defect is disorder of low progesterone secretion (low level), or very short luteal phase (shorter than 11 days). Consequence of that is late endometrium maturation, almost 2 days. Such endometrum impedes and makes impossible ovum nidation. Today we have luteal phase defect in 14% of infertility women, and in 21% of women of unknown infertility reason. This has been frequently seen in women with spontaneous abortion and hyperprolaktinemia. Diagnostic methods of DLF are biopsy of endometrium and measuring of progesterone level. The aim of this study is the examine endometrium maturation disorders. The study includes 30 women that are hospitalized in Clinical of Gynecology Pristina. Unknown reason of infertility and normal hormonal status had been in 13 (43%), and hyperprolaktinemia in 7 (56,7%) of women. Histological verificated ovulation had been finding out in 60%of women. Late endometrium maturation, luteal phase defect, had been verificated in 23,3% of women, from there in 29,4% of hyperprolaktinemic women and in 5,4% of women of unknown infertility reason. There was evidence of late endometrium maturation of 2 days (85,7%). and of 4 days th (5,4%). Progesterone level in DFLthe 20th day was 30 nmol/l, the 24 day of menstrual cycle was 28,8 nmol/l. Progesterone level in women with histological proved regular endometrium maturation was higher and it was 45, nmol/l. The lowest progesterone level that can be find in good functioning of luteal body was 31,8 nmol/l.Citohormonal findings in DFL was showing progesterone domination. Take a look at infertility and ovarian function must not be concern only on ovulation, it must take care of endometrium maturation.

The aim of the work is to study the development of twin pregnancy after one of twins died in early pregnancy and
possible negative influence on clotting system of pregnant women. Observation is done on patient DM, 30 years old, and
housewife. She was observed from her first appearance at the department. Personal and family anamnesis was regular. She
had one delivery tree years ago with Cesarean section. In the first ultrasonographic examination we found twin pregnancy
with obvious heartbeats of both twins. After two weeks on control examination we find only one fetus, regularly developed,
and in a separate amniotic cavity a fetus without heart beat with small quantity of amniotic fluid in bizarre position. Patient
was immediately admitted in the hospital. Ultrasonographic examination, as well as a routine laboratory analyses were
repeated every ten days. After 28-th week of gestation we included a cardiotocographic (CTG) control every five days. In
38-th week the birth was finished by cesarean section (indication for operation - previous cesarean section). Afemale child
was born. After delivery, placenta was extracted with membranes, which contained a dead fetus, 12-cm length. After
recovery which lasted seven days patient was dismissed in good condition with healthy baby. An ultrasound examination
proved to be of great help in putting a diagnosis. It is very important to put diagnosis in time, because if we don't do it, we
will probably have a great and heavy complication.