Gastrointestinal stromal tumors (GIST omi) are a heterogeneous group of mesenchymal tumors. Etiological factors that cause GIST ome are not clearly distinguished, characterized by remarkable diversity of the clinical, histopathological and genetic features. Mitotic activity, nuclear pleomorphism, degree of cellularity, nuclear-cytoplasmic ratio, tumor size, mucosal invasion, tumor ulceration and necrosis, are factors that determine the malignancy of these tumors. The most common location of these tumors of the stomach and small intestine, while very rare localization of the colon, esophagus and rectum. Despite the progress that has been made in the diagnosis and further diagnosis of intra - or postoperative. The aim of this report is to contribute to easier recognizing the symptoms, diagnosis and treatment of these tumors. It was a mixed tumor, epitheloid-spindle type cells, immunohistochemical analysis, we have a positive expression of CD 117 and CD 34.

The importance of the examination of life quality of children having asthma is more and more emphasized in the world. Asthma is a disease which limits the persons having this disease in physical, social and mental activities. Information about life quality can only be obtained by the patients because only they have direct insight into their feelings and thoughts. Our research included 95 children having allergic asthma and 40 children having nonallergic asthma were examined. Questionnaire on life quality of children having asthma in the case of general activities PAQLQ(S), whose creator is prof. Elizabeth Juniper, was used for the examination of life quality. The results were shown by questionnaire scores (total and individual ones). Determination of the activities representing the biggest restraints in the life of examined patients gives the possibility for adequate carrying out of therapy as well as better education of the patients concerning self-control of disease.

Bacterial meningitis is an important medical problem, as because of the use of powerfull antibiotics and other
drugs, and therapeutic measures, the number of patients, as well as the mortality haven't been changed for years. Because of that the study of pathogenesis of bacterial meningitis has been one the most dynamic researsh fields in recent years. Meningitis caused by salmonella is not usual clinical manifestation of salmonella infections, but because of fulminant evolution and specific structure of cause. Path and effect of diseases, it deserves special attention. Our researches encompases 29 children who suffer from salmonella meningitis. Out of the whole number of cured children, the moust frequent was at newborn (58,6%), while the smallest number was in the group of older infant (6.9%). Concernig the sex structure of diseased, the biger number was at male (62.0%). The most important finding in liquor cerebrospinalis at patients is polymorphonuclear leucocytosis (average value of cell elements is 3744, with 82% polymorphonuclears). At the same time existed leucocytosis in peripheral blood with sigificant deviation into left. At all our patients hypoglycorachya expressed (1.45mmol/L). The value of proteinorachya was 1.71 g/L. The result of the disease was successful in 49.3%, died 24,1%, and cured with consequences 27,6%.