Intussusception is a specific type of delay in the bowel passage which according to frequency, clearly takes place in children's abdominal surgical pathology. Most commonly occurs in children during the first year of life and from 6 and 9 months where the 3 diagnosed in boys than girls 2. The incidence is 1-4 per 1000 live-born children. The most common form of invagination is ileocecala (80%), ileocolic, and ileo-ileal colo-colic. Intussusception is most often idiopathic (almost 90%) cases, while in a very small percentage described the existence pathoanathomic substrate (points leaders), which areusually enlarged lymph nodes or Meckel divertikulum. Surgical therapy for these other groups is much more radical. For a period of 6 years (2003-2009), which we cover the work, the children’s surgery of the Health Center Novi Pazar was treated with 22 children diagnosed with invagination (intussusception). Of this number, there were 14 (63.63%) boys, 8 girls (36.36%), and the average number of cases was 4.44 per year. Frequently appeared ileo-cecal and ileo-ileal (90.63%), while colocolic and ileocolic appeared much less (9.09%). The most common clinical symptoms were the presence of fresh blood in the stool, painful cramps and, vomiting who did the dominant clinical presentation in the majority. Following: fever, malaise, and even convulsions. The conclusion is: triad of symptoms (pain, vomiting and blood in the stool in the form "of currant jelly") were pathognomonic diagnosis. The method of choice in the diagnosis and conservative therapy is the initial hydrostatic desinvagination controlled ultrasound.

Prostatic intraepithelial neoplasia (PIN) is putative premalignant lesions of the prostate. This lesion has role as precuror of prostatic carcinoma (PC), predictive role for PC and high coexistens with PC. Existed two grade of PIN: low grade PIN (LGPIN) and high grade PIN (HGPIN). PC is most important malignacy in man and has high mortality in male. The aim of research was to invastigated morphological comparative patterns of HGPIN and PC. We analyzed biopsy material of 299 cases (cs). We used histopathological metods of investigation. We found HGPIN in 42 cs (14.0%) with mean age 66.3 y and PC in 35 cs (11.7%) with mean age 70.7 y. HGPIN was most frequently in the seventh decade of life (54.8%), and PC in the eight decade (45.4%). Four common pattern of HGPIN were identified: tufting (78.6%), micropapillary (72.8%), cribriform (16.6%) and flat (9.5%). In 21 from 35 cs (60%) with PC was coexistent HGPIN. HGPIN we found in the periferial part in the 22 cs. (52.4%) and in the periurthral part of the prostate in the 12 Cs. (28.6%). HGPIN were multicentric in the 22 cs. (52.4%), in the 15 cs. (68.2%) in the periferial part, and in the 7 cs (31.8%) in the periurethral part of the prostate. PC in the 22 cs (62.9%) was localized in the periferial, and in the 7 cs in the periuretral portion of the prostate. PC was multicentric in 28.6%. Important histological patterns for distinction HGPIN i PC are: disruption of basal cell layer, perineural invasion, mitotic figures, multiple nucleoli, collagenous micronodules, infiltrative growth. HGPIN and PC we found in sufficient percentage. Both lesion were most frequently multicentric, periferial localisation and coexistent. Because of that these lesions needed serious clinical and histological investigations for patients.