Current issue
Volume 53, Issue 4, 2025
Online ISSN: 2560-3310
ISSN: 0350-8773
Volume 53 , Issue 4, (2025)
Published: 30.06.2025.
Open Access
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Contents
15.02.2025.
Case Reports
VITAMIN D - „SOLAR VITAMIN“
The discovery that sunlight can cure rickets was first scientifically confirmed in 1919. Shortly thereafter, in 1924, it was found that inactive lipids in the diet and skin are converted into antirachitic substances under the influence of UV light. Vitamin D (Vit D), also known as the "sunshine vitamin,"
was first identified in 1931. In recent decades, it has regained the focus of interest among the broader scientific community and dermatologists.
Specifically, certain dermatoses have been associated with low Vit D levels, leading to its supplementation in patients. On the other hand, some
dermatoses worsen with sun exposure, necessitating strict avoidance of sunlight and the therapeutic use of Vit D preparations.We are witnessing a
growing number of cases of melanoma and non-melanoma skin cancers, with excessive sun exposure being the primary etiological factor in most
cases. This paper provides a literature review on the historical discovery of Vit D and presents findings from studies examining Vit D levels not only in
various dermatoses but also in other diseases. The number of studies, as well as the spectrum of diseases in which the role of Vit D is being
investigated, continues to increase.
Milijana Relić, Snežana Relić, Tanja Kostić Grujić, Marijana Trajković, Zorica Timotijević, Tamara Jovanovic, Goran Relić
15.02.2025.
Professional paper
EXAMINATION OF INTRACRANIAL TRANLUCENCY AS A MARKER FOR EARLY DETECTION OF OPEN SPINA BIFIDA
This article focuses on the sonographic axamination techique for evaluation of intracranial translucencies during the first trimester ultrasound scan. Appropriate knowledge of sonographic landmarks is the most important factor for evaluation normal as well as abnormal brain structure, and this examination may enable detection of open spina bifida and Arnold – Chiari anomaly at an early stage of fetal develpoment.
Nenad Šulović, Goran Relić
01.12.2019.
Professional paper
Frequency and histological-cytological correlation of premalignant and malignant changes in the cervix in women of different ages
Introduction: Cervical cancer is the fourth most common and accounts for about 6.6% of all cancers in women. Aim: The aim was to determine the frequency of premalignant and malignant changes in the cervix, to examine the histological-cytological correlation of premalignant and malignant changes in the cervix and the correlation of the women's age with the stage of cervical disease. Material and Methods: A retrospective study analyzed 186 cervical biopsy specimens and cervical smears (Papanicolau test) at the Institute of Pathology of the Faculty of Medicine in Pristina, based in Kosovska Mitrovica, over a three-year period from 2016 to 2018. Results: Of the 186 subjects, 62 had mild premalignant changes of type LSIL, 22 HSIL, and as many as 20 (10.75%) cervical cancer. There was a statistically significant positive association between histological and cytological findings (r = 0.854; p <0.001). There was a statistically significant difference in the age of the subjects with regard to histological findings (F = 11,327; p <0.001). Subjects with HSIL were significantly older than those diagnosed with cervicitis chronica (p = 0.029). Subjects diagnosed with planocellular carcinoma were significantly older than women with cervicitis chronica (p <0.001) and LSIL (p <0.001). Conclusion: There is an increasing trend of cervical cancer in Northern Kosovo and in the Serbian enclaves in central Kosovo and Metohija. Subjects with cervical cancer were significantly older than subjects with mild premalignant cervical changes. There is a significant histologic-cytological correlation of cervical findings, so we believe that more massive cervical screening, especially in younger women, could reduce the incidence of premalignant and malignant diseases of the cervix.
Dejan Mihajlović, Zoran Bukumirić, Nenad Šulović, Goran Relić, Slaviša Stanišić, Saša Cvetković, Momir Dunjić, Tanja Mirković, Milica Milentijević, Novica Đoković, Mirjana Stojanović-Tasić
01.12.2019.
Professional paper
Mehanizam kontrakcije i relaksacije miometrijuma, interakcija okcitocina i prostaglandina
Goran Relić, Vujadin Mujović, Nenad Šulović, Slaviša Minić