The objective was to determine the type of venom poisoning causes accidental, sex, age, occupation, place where the poisoning and seasonal distribution. The work was carried out comparative analysis of accidental poisoning in Belgrade in two five-year period 1965th to 1969. and since 2000. by 2004. year. The structure accidental poisoning in the first mentioned period dominated by gas poisoning (CO) and alcohol, and in the second period, poisoning psychoactive substances. In both the five-year period were more likely to be poisoned males. In the first study period, were often poisoned persons older age groups, while in the second period there was a shift to younger age groups. Between 1965 and 1969 and were significantly more frequent poisoning among farmers compared to the period 2000-2004, when they are significantly more common poisoning in students and the unemployed. The highest percentage of poisoned in both investigated period, was found in our own home with no signs of life. Accidental poisoning occurred more frequently in the winter months in the first study period, while in the second period seasonality is not expressed.