Future unavoidable development of individualized brain anatomy as a part of personalized medicine requires large databases from a vast number of individual brains. The simple descriptions, important in the clinic, demonstrated the wide morphological and morphometric variability of the sulci and gyri. Today, it is no longer enough, like in traditional anatomy, to simply describe one single, several, or even "all" sulcal/gyral variations in one region of the brain. Potential problems in the comprehensive analysis of their patterns with attempts to suggest further research are briefly reviewed. The medial hemispheric surface is suitable for a morphological pilot study of complete sulcal and gyral variability. Sulcal patterns should be presented in simplified linear form rather than as detailed images, and one useful simplification for analyzing gyral patterns, the essential gyral line, is described. Simultaneous investigation of gyri and sulci is recommended, but the problem is combinations of specific patterns in different percentages. Sophisticated algorithms could recognize cortical patterns and calculate their possible combinations. Anatomical terminology is an unavoidable component of these studies. Big data about variations of sulci and gyri would be useful in personalized medicine but also in genetic studies of potential laws and inheritance of their associations.

In article is discussed, from the viewpoint of anatomist, the absence of a "standard" anatomical terminology in Serbian language and the consequences of this fact. After a short overview of the history of the anatomical terminology in the world, the importance of standard anatomical terminology in communication and accurate data exchange in medicine are highlighted. Brief history and the difficulties in the development of anatomical terminology in the Serbian language are presented, and the important role of linguists in its preparation is emphasized. Finally, the reasons why it is necessary to establish a standard anatomical terminology in the Serbian language are given. These reasons are: 1. During the study of anatomy, students encounter new concepts for the first time, which are best explained to beginners in Serbian language; 2. in order to facilitate learning, it is important that texts in anatomy textbooks and from various branches of medicine do not contain different names for the same structures; 3. for entering data into the computers that are now widely used, it is very often necessary to enter the specific terms correctly; 4. general literacy and standardization of professional language should not be neglected, while preserving traditional expressions that patients should also understand; 5. creating a unique terminology avoids arbitrary creation and use of names; 6. finally, the future anatomical terminology in the Serbian language can also serve as an aid to translators in translating to and from Serbian.