The objective of this study that included 34 patients with psoriasis was to assess the reliability of the disease severity measures (i.e. Psoriasis Area and Severity Index - PASI) and the reliability of the health related quality of life measures (i.e. EuroQol EQ-5D Quality of Life Scale - EQ-5D, Dermatology Life Quality Index - DLQI and Psoriasis Disability Index -PDI). High interobserver correlation reliability and good test-retest reliability of PASI scores, as well as good test-retest reliability of EQ-5D, DLQI and PDI scores were achieved. Correlation coefficients between the test and retest scores on DLQI and PDI were higher than those on the dimensions and on EQ-VAS in EQ-5D. Disease severity scores given by PASI and the quality of lify scores given by EQ-5D, DLQI and PDI offered the reliable assessment of both the psoriasis severity and the quality of life of the people with psoriasis.

Condylomata gigantea is an expansive, destructive lesion that affects most frequently anal and perianal region, and
rarely vulvar and vaginal region. We will describe a clinical case of a 28 years old female patient with a diagnosis of Condylomata gigantea in anal and perianal region with propagation on vulva, vagina and clitoris. After we detected a wide base of condylomas in anal and perianal region, we performed a deep, multiple biopsy for discover of eventual malignancy.
Histologically, malignancy was not confirmed, but it was discovered a presence of HPV types 6 and 11. The patient was initially treated with a wide surgical excision, and then the rest of condylomas were removed using CO laser which had an 2
haemostatic function in the same time. Three months later, there was no recurrence.