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Volume 53, Issue 4, 2025
Online ISSN: 2560-3310
ISSN: 0350-8773
Volume 53 , Issue 4, (2025)
Published: 30.06.2025.
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Contents
30.06.2025.
Professional paper
ZNAČAJ HISTEROSKOPIJE U DIJAGNOSTICI I LEČENJU UROĐENIH ANOMALIJA KAVUMA UTERUSA
SAŽETAK
SAŽETAK
Uvod: Histeroskopija predstavlja jednu od važnih endoskopskih metoda u ispitivanju morfologije i funkcionalnosti materice, kao uzroka infertiliteta.
Uterusni faktor je zastupljen kod 10% infertilnih žena, pri čemu promene u materici mogu biti urođene i stečene.
Cilj: Cilj rada je da se proceni značaj histeroskopije u dijagnostici i tretmanu urođenih anomalija materične šupljine, kod pacijentkinja kod kojih
postoji osnovana sumnja na osnovu prethodnog kliničkog, ultrazvučnog i histerosalpingografskog (HSG) pregleda. Značaj histeroskopije će biti
posmatran u odnosu na broj ostvarenih trudnoća u zavisnosti od dijagnostikovane anomalije u periodu od 12 meseci, nakon obavljene histeroskopije u
dijagnostičke ili operativne svrhe.
Metode rada : Studijom preseka obuhvaćene su 176 pacijentkinja sa kongenitalnim anomalijama materice kod kojih je urađena histeroskopija. Kod
svih pacijentkinja je praćen procenat nastalih trudnoća u toku prvih 12 meseci posle operacije. Tako su dobijene dve grupe pacijentkinja- koje su
ostvarile trudnoću i one koje nisu, čije su karakteristike uporedjivane.
Rezultati : U sprovedenom ispitivanju srednja životna dob ispitivanih pacijentkinja iznosi 35. god. Grupu ispitanica sa primarnim infertilitetom čini
ukupno 107 pacijentkinja, dok je 69 ispitanica sa sekundarnim infertilitetom. Prosečna dužina trajanja infertiliteta kod ispitivanih pacijentkinja je 3
god. Svega 3% ispitanica imaju prethodne uspešne trudnoće. U periodu od 12 meseci su posmatrane ispitanice i kod 39 (22%) je došlo do trudnoće,
koja je kod 33 ispitanice završena porođajem u terminu. Hi kvadrat testom je dobijena statistička značajnost (p<0.05) između posmatranih grupa
ispitanica u zastupljenosti vrste infertiliteta, kao i u broju prethodnih pobačaja.
Zaključak: Od svih kongenitalnih anomalija materice, najzastupljenije su uterus subseptus i septus. U našem istraživanju 20% ispitanica su ostvarile
trudnoću nakon histeroskopije u posmatranom periodu od 12 meseci, dok je kod većine njih trudnoća završena porođajem u terminu. Procenat
pobačaja kod ispitivanih žena smanjen je sa 38% pre histeroskopije na 15% nakon histeroskopije. Kod žena koje su ostvarile trudnoću većinom su
dijagnostikovani septum i subseptum uterusa i rađena je histeroskopska resekcija promena.
Ključne reči: histeroskopija, kongenitalne anomalije uterusa, trudnoća
Milena Šaranović
01.12.2019.
Professional paper
The role of computerized tomographic angiography in the diagnosis of pathologically modified renal arteries
Introduction: The most common causes of renal artery disease are stenosis, as a consequence of atherosclerosis and fibromuscular dysplasia. Computed tomographic (CT) angiography is a non-invasive method, which enables visualization of vascular structures and walls of blood vessels, as well as morphology of the renal parenchyma. Objective: To determine the importance of CT angiography in detecting the cause and degree of renal arterial disease. Methods: A total of 45 patients were included in the cross-sectional study conducted from March 2017 to March 2019 in the KBC DR Dragiša Mišović-Dedinje, Belgrade, Serbia. Criteria for inclusion were suspicion of secondary arterial hypertension, patients in preparation for kidney transplantation and in the follow-up period after transplantation, as well as patients with suspected traumatic lesions. We analyzed the causes of the disease, the morphology of the blood vessel wall, the percentage of stenosis, and the renal parenchyma. Results: The most common causes of renal arterial disease are atherosclerosis, which was found in 33 (73%) patients, renal artery aneurysm was found in 5 (11%) subjects, fibromuscular dysplasia in 4 (8.9%) and trauma in 1 (2) , 3%) of the patient. There were 10 (22.2%) patients with a significant (average 80 ± 14.5%) degree of stenosis. The sensitivity of CT angiography in the detection of atherosclerotic changes in the renal arteries was 87.9%, while the sensitivity of CT angiography in the detection of fibromuscular dysplasia was 75%. A statistically significant correlation was found between atherosclerotic stenosis of the renal arteries and a positive CTA finding (p = 0.0002). Conclusion: CT angiography is an important method of visualization and quantification of pathological changes in the renal arteries.
Miloš Gašić, Sava Stajić, Ivan Bogosavljević, Milena Šaranović, Aleksandra Milenković, Sanja Gašić
01.12.2017.
Professional paper
The importance and role of echotomographic examinations in malignant altered axillary lymph nodes
Introduction: The presence of malignant altered axillary lymph nodes, and their timely detection is crucial for staging and prognosis of breast cancer. Echotomographic examinations are widely used technique, and represents one of the first tests of diagnostic modalities. Classic B mode, Doppler sonography, and MicroPure testing technique, allow a comprehensive assessment of the detailed morphology and internal structure of the nodes (number, location, size, shape, borders, echogenicity, edema of the surrounding soft-tissue, the presence of microcalcifications), and determination of their nature. Objective:The aim is to determine the role of echotomographic review the morphology, determining the nature and setting guidelines for diagnostic testing algorithm for malignant altered axillary lymph nodes. Materials and methods: This cross-sectional study included 212 echotomographic tested axillary lymph nodes in the Department of Radiological Diagnostics KBC "Dr Dragisa Mišović-Dedinje" in Belgrade, in the period from February 2016.do March 2017. All patients were examined in the supine position with arms in abduction, and external rotation. The following parameters: shape, size, and homogeneity of the echo-structure, edge, an auxiliary structures such as intranodal necrosis, edema and peripheral vascularization, as well as the presence of microcalcifications, using classical B mode, Doppler sonography and MicroPure technique. For all examinations we used Toshiba device, Aplio XG, 10MHz linear transducer. Results: Of a total of 212 tested nodule, histopathology was also verified 44 malignantly changed (21%), 4 of which the primary (9%) in a patient with Hodgkin's lymphoma, and secondary 40 (91%) in patients with breast cancer. Other nodes 168 (79%) were normal-reactive. The best performance in the echotomographic examinations are the criteria of: the shape (longitudinal cross-ratio <2) with a sensitivity of 86.9%, presence of microcalcifications with sensitivity of 83,7%, hilus (not clearly defined, and hypoechogenic) with sensitivity of 81.8%, the size (transverse diameter greater than 8mm), with a sensitivity of 79.2%, as well as echogenicity (hypo to anechogenic) with sensitivity of 73.1%. Conclusion: Echotomographic review is a useful imaging modality in evaluating the morphology and nature of axillary lymph nodes, but none echotomographic criterion in itself is not enough reliable in evaluating malignancy. Meticulousness when reviewing and examining all the criteria and modalities (B mode, Doppler, MicroPure) remain imperative in the diagnostic algorithm of tests axillary lymph nodes.
Miloš Gašić, Ivan Bogosavljević, Bojan Tomić, Milena Šaranović, Aleksandra Milenković, Sava Stajić