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Volume 53, Issue 4, 2025
Online ISSN: 2560-3310
ISSN: 0350-8773
Volume 53 , Issue 4, (2025)
Published: 30.06.2025.
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Contents
30.06.2025.
Professional paper
HEPATOPROTEKTIVNA SVOJSTVA SURUTKE NA OŠTEĆENJE JETRE IZAZVANO ALKOHOLOM
Uvod: Alkoholna bolest jetre predstavlja globalni zdravstveni problem, sa kompleksnom patogenezom koja uključuje oksidativni stres, inflamaciju i
poremećaj metabolizma lipida. Surutka, kao prirodni proteinski kompleks, vekovima se koristi u ishrani i tradicionalnoj medicini, a svojim
jedinstvenim sastavom može imati protektivno dejstvo na jetru. Ovaj rad sistematizuje dosadašnja saznanja iz literature o potencijalnim
hepatoprotektivnim efektima surutke u kontekstu alkoholne bolesti jetre.
Glavni deo rada: Ključne komponente surutke, uključujući laktoferin, beta-laktoglobulin i alfa-laktalbumin, pokazuju antioksidativne,
antiinflamatorne i imunomodulatorne osobine. Surutka može delovati na više nivoa: (1) povećanjem kapaciteta antioksidativne odbrane stimulacijom
enzima kao što su superoksid dismutaza i katalaza, (2) modulacijom inflamatornih puteva inhibicijom NF-κB i smanjenjem proizvodnje TNF-α i (3)
poboljšanjem metabolizma lipida u hepatocitima. Posebno se ističe visok sadržaj cisteina, vodećeg za sintezu glutationa – najvažnijeg endogenog
antioksidansa u jetri. Istraživanja na životinjama ukazuju da suplementacija surutkom može sprečiti nastanak steatoze i fibroze, dok su podaci iz
kliničke prakse još uvek ograničeni.
Zaključak: Prema dostupnoj literaturi, surutka se pokazala kao potencijalni prirodni agens u prevenciji i podršci lečenju alkoholne bolesti jetre. Ipak,
potrebna su dodatna klinička istraživanja kako bi se njena efikasnost kod ljudi potvrdila, budući da su postojeće studije uglavnom sprovedene na
animalnim modelima.
Ključne reči: surutka, alkoholna bolest jetre, antioksidansi, inflamacija
Ivan Radić, Biljana Zogović
01.12.2020.
Professional paper
The role of the electrocardiogram in identifying the risk of sudden cardiac death
Introduction: Sudden cardiac death (SCD) represents the unexpected and sudden death of young apparently healthy people. Alarge number of examined cases referred to professional athletes. There is not enough data in the literature related to those who performed sports in a sporadic and recreational manner. In order to prevent SCD, a screening protocol was determined, in which, an ECG performed at rest plays a important role. Based on the established criteria, changes on the ECG can be treated as normal, borderline and abnormal. An abnormal result indicates a risk of SCD. Objective: The aim of this study was to determine the risk of SCD in students who practice physical activity recreationally. Methods: The research involved 500 students (both sexes) of the 1st and 3rd year of study on the University of Pristina situated in Kosovska Mitrovica. As part of the regular systematic examination, an ECG was performed at rest. The risk of SCD was determined by analyzing the changes on the ECG and grouping them based on screening recommendations. Results: The obtained results show that 44% of students had changes on the ECG and that 8% of students had an abnormal result indicated a possible risk of sudden cardiac death. Conclusion: Therefore, timely recognizing and interpreting ECG changes in accordance with screening recommendations is an imperative for identification and possible prevention of SCD.
Biljana Zogović, Miljan Stašević, Ivan Radić
01.12.2016.
Professional paper
Antioxidative features of whey and its application in liver protection
Ivan Radic