Chronic vein insufficiency (CVI) is abnormal functioning of a system of veins resulted from incompetence of vein valves, with or without vein obstruction covering both surface and deep veins. Nowadays there are various standars in the diagnosis of CVI and variations of treatment modalities, which increases the importance of occuracy and foundations of the diagnosis. In the consideration of diagnostic needs of patients with CVI, CEAP classification is suggested. This classification defines clinic categories, etiology of problem, covered anatomical segments and pathological mechanisms of CVI.

Breast cancer is mostfreqency malignant tumor in womans, cardinal causer of death in malignant tumots with continous ascendig of incidence and mortality. Actual therapy of breast cancer is multidisclipinary to consist in surgical, irradiant, cytostatic, hormonal and imunological therapy with specific directive based in disease stage. Surgical therapy is now more effectiveness metod of therapy and base of multidisclipinary therapy. In aim of prognosis desease conclusion and risk ratio of local relapse in currency is prognostic factors. With combination a few factors derive prognostic indexes with whose can acquire more information aggainst biologic behaviour of each neoplasm.

Getting on in years individually becomes the biggest risk factor in appearance of the woman's brest cancer. From the entire number of new discovered woman's breast cancers, 48% are women older then age of 65. Woman's breast cancer discovered by persons got on in years diagnose in getting forward condition of illness besides bigger cancer freqvency with propitious histology and biological profile. There are not enough proper studies about the breast cancer in elderly. For the project development material has been used from the surgical clinic and clinic for Oncology, as wellas institute for Pathology of the clinical centre in the city of Nis.The data from our serial direct attention to rarer conduct of standard diagnostic procedures at elderly with breast cancer. Also the conectivity between years of the patients; and time being passing from the initial diagnosis until treatment has been studied. Using pathhistology exam we were reseiving information about histological type of cancer, about the size of cancer, histological and nuclear grade, as well as absence or hold of metastasis process of lymph nodus. The most frequent used surgical procedure was radical mastectomy modified by Madden and Patey. The presence of complications has been tracked in the postoperative progress. In the postoperative progress depending on condition of breast cancer histological and nuclear grade, hold of the lymph knots,positivism of hormonereceptors, presence of comorbidity female patientswere subjected to adjuvant therapy. With purpose of perception of diagnoses as well as caracteristics and results of treatment of the female patient's survival has been tracked. The average survival in the examined group was 21 months while it was 31 month in the control group