29 - year Lichen planus is a chronic, inflammatory, autoimmune skin disease, that is often manifested, except on the skin, in the oral cavity in a variety of clinical forms. The prevalence of the disease in the general population is about 1-2%. Etiopathogenesis is not still well understood. Histopathology, in addition to the basic methods, anamnesis and physical examination, is vital for proper diagnosis of oral lichen planus (OLP). Very diverse and loaded histological findings are common for all forms of oral lichen planus. We reported the case of oral lichen planus in a 49 years old male patient, who presented to the Dentistry clinic of Medical faculty of Priština with burning and itching symptoms and changes in the buccal mucosa. Histopathological analysis of biopsy tissue conformed clinical diagnosis of lichen planus. Due to the possibility for malignant transformation of lesions, the long-term follow-up of patients with this disease is of great importance.

In diabetics fungal skin infections are reported to be related to greatly disturbed metabolism. In order to get better insight into the association between diabetes mellitus and fungal skin infections, we started our study with the aim to assess the effect of metabolic regulation on the incidence of fungal skin infections is diabetics. The obtained results of our study show that in patient with metabolically poorly regulated primary disease i.e. diabetes the incidence of the fungal skin infections is highest (36.0%), its incidence is lower in patients with metabolically satisfactorily regulated diabetes (29.5%) and lowest in those with well regulated diabetes (18.8%), witch is statistically significant difference (p=0.045).

Diabetes mellitus is a typical example for connection betwen sickness of internal organs and the skin. The ratio betwen glycose level in a gram of skin and the amount of glycose in a mililiter of blood is higher in diabetes mellitus then normal. This implies that insulin regulates intracelular distribution of glycose in the skin. It is recessary for the keratinocyt growth and diferentiation, healing of wounds, but also for the fibroblast functioning in the derm. In diabetes mellitus acidofil is lowered, and glycolised colagen is increased, and fibroblasts in the extra produce fibronectin. Skin and visible mucosys infections caused by candida albicans in diabetes patients belong to the group of deseases that could be a consequence of a disbalanced metabolism. They are seen frequently, but not patognomic for these patients, becuse they are also possible in people whose metabolism is normal. Badly controlled or undiagnosed dibetes mellitus is often coupled with candida induced skin deseases. Sometimes candida infections are the first sign of diabetes. Dermatologist is often in position to discover the disease on the basis of skin symptoms, which gives possibility for regulation of the sickness on time and avoid complications. It is known that complications develop slower when diabetes is regulated. Skin alterations in candidiasys and its connection with diabetes are described briefly, with an attempl to explain patogenesys of their apearence.