Change in left ventricular volumes, particularly end-systolic volume index is a major representative of left ventri cular dilatation, and is a predictor of mortality after acute myocardial infarction of anterior localization. Several large-scale trials have demonstrated beneficial effectiveness of ACE inhibitors on the process of left ventricular remodeling after myo cardial infarction, not only in patients with compromised systolic function. Aim of the study was to evaluate the influence of therapy for ACE inhibitors in the early faze of anterior myocardial infarction, trough dynamics of left ventricular volume in dexes. During six months 30 patients were evaluated with echocardiography in admission, before leaving the hospital, after
three and six months after myocardial infarction. In evaluated group there was increased end-diastolic and end-systolic vo lume index, but without statistically significant value. There were no new cardiac decompensations. We concluded that ACE inhibitors given in the early stage of acute myocardial infarction anterior localization have beneficial effect on the process of left ventricular remodeling and that is recommended to bee given to this patients, after excluded contraindications