Introduction: Diabetes mellitus is a metabolic disorder syndrome with the presence of hyperglycemia, which is in turn caused by reduced insulin secretion, reduced biological effect of insulin, or both. It is certainly one of the most common endocrinological diseases of the modern way of life. Diabetes mellitus is a problem for every society. It is a chronic illness that people of all ages suffer from, regardless of their sex. It is believed that there is a "World Epidemic of Diabetes". Diabetes mellitus, with its chronic complications, is the cause of a significant percentage of morbidity and mortality among the population. In 2011, Serbia was among the countries with high rates of of death from diabetes. Case outline: Male, a longtime diabetic and former smoker. The mother was a longtime diabetic and hypertonic. Conclusion: Chronic complications of diabetes represent a major medical, social and economic problem and significantly impair the quality of life of the patient. Screening for the detection of persons at risk of developing diabetic foot is performed at the primary level of health care by mandatory examination at least once a year. Patient education is of particular importance. The patient should be alerted to the reduced protective sensibility (thermal, mechanical and chemical agents), the need for daily foot inspection, adequate foot hygiene, including skin and nails, and wearing appropriate footwear.